ID   OP28_NEIGO              Reviewed;         234 AA.
AC   P11297;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Opacity protein V28;
DE   Flags: Precursor; Fragment;
OS   Neisseria gonorrhoeae.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3093085; DOI=10.1016/0092-8674(86)90366-1;
RA   Stern A., Brown M., Nickel P., Meyer T.F.;
RT   "Opacity genes in Neisseria gonorrhoeae: control of phase and antigenic
RT   variation.";
RL   Cell 47:61-71(1986).
CC   -!- FUNCTION: Implicated in a number of adherence functions. OPA proteins
CC       are implicated in pathogenesis and are subject to phase variation.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC   -!- SIMILARITY: Belongs to the opacity porin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M14747; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; B24429; KONH8.
DR   AlphaFoldDB; P11297; -.
DR   SMR; P11297; -.
DR   Reactome; R-HSA-202733; Cell surface interactions at the vascular wall.
DR   GO; GO:0009279; C:cell outer membrane; TAS:Reactome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:InterPro.
DR   InterPro; IPR006315; OM_autotransptr_brl.
DR   InterPro; IPR011250; OMP/PagP_b-brl.
DR   InterPro; IPR003394; Porin_opacity.
DR   Pfam; PF02462; Opacity; 1.
DR   SUPFAM; SSF56925; SSF56925; 1.
DR   TIGRFAMs; TIGR01414; autotrans_barl; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          <1..1
FT                   /evidence="ECO:0000255"
FT   CHAIN           2..>234
FT                   /note="Opacity protein V28"
FT                   /id="PRO_0000021900"
FT   NON_TER         1
FT   NON_TER         234
SQ   SEQUENCE   234 AA;  26771 MW;  339AEB09C2FE75E4 CRC64;
     AGEDHGRGPY VQADLAYAYE HITHDYPEPT GTKKDKISTV SDYFRNIRTH SIHPRVSVGY
     DFGGWRIAAD YARYRKWNDN KYSVDIKELE NKNQNKRDLK TENQENGTFH AVSSLGLSAV
     YDFKLNDKFK PYIGARVAYG HVRHSIDSTK KTTKFLTSSY GGLNPTVYTE ENTQNAHHQS
     NSIRRVGLGV IAGVGFDITP KLTLDAGYRY HNWGRLENTR FKTHEASLGV RYRF