ID   OPA3_DANRE              Reviewed;         157 AA.
AC   Q1L9A2;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Optic atrophy 3 protein homolog;
GN   Name=opa3; ORFNames=si:dkey-12o15.3;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
CC   -!- FUNCTION: May play some role in mitochondrial processes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OPA3 family. {ECO:0000305}.
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DR   EMBL; CR377223; CAK05152.1; -; Genomic_DNA.
DR   RefSeq; NP_001073635.1; NM_001080166.1.
DR   AlphaFoldDB; Q1L9A2; -.
DR   STRING; 7955.ENSDARP00000082921; -.
DR   PaxDb; Q1L9A2; -.
DR   Ensembl; ENSDART00000088488; ENSDARP00000082921; ENSDARG00000061761.
DR   GeneID; 497278; -.
DR   KEGG; dre:497278; -.
DR   CTD; 80207; -.
DR   ZFIN; ZDB-GENE-050210-1; opa3.
DR   eggNOG; KOG3335; Eukaryota.
DR   GeneTree; ENSGT00390000009795; -.
DR   HOGENOM; CLU_074707_5_1_1; -.
DR   InParanoid; Q1L9A2; -.
DR   OMA; KTYVCLP; -.
DR   OrthoDB; 1444400at2759; -.
DR   PhylomeDB; Q1L9A2; -.
DR   TreeFam; TF314653; -.
DR   PRO; PR:Q1L9A2; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 18.
DR   Bgee; ENSDARG00000061761; Expressed in cleaving embryo and 36 other tissues.
DR   GO; GO:0005739; C:mitochondrion; IDA:ZFIN.
DR   GO; GO:0007626; P:locomotory behavior; IMP:ZFIN.
DR   GO; GO:0050881; P:musculoskeletal movement; IMP:ZFIN.
DR   GO; GO:0031413; P:regulation of buoyancy; IMP:ZFIN.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IBA:GO_Central.
DR   InterPro; IPR010754; OPA3-like.
DR   PANTHER; PTHR12499; PTHR12499; 1.
DR   Pfam; PF07047; OPA3; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Mitochondrion; Reference proteome.
FT   CHAIN           1..157
FT                   /note="Optic atrophy 3 protein homolog"
FT                   /id="PRO_0000326548"
FT   COILED          103..129
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   157 AA;  17306 MW;  9223CBFCA08FEFBA CRC64;
     MVVGAFPIAK LLYLGVRQLS KPVANRIKAG ARRSEFFKNY ICLPPAQAYH WIEMRTKMRI
     MGFRGSTIKP LNEDAAAELG AELLGEAIIF VIGGGCMVLE YSRQAANSRR KEEELAQSIT
     SLQTQLGELA LTTETLDAQI REVNRLLLSL PAAPSSK