OPAP_DROME
ID OPAP_DROME Reviewed; 83 AA.
AC P23488; Q9VNV8;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Male-specific opa-containing protein;
DE AltName: Full=Protein dromsopa;
DE Flags: Precursor;
GN Name=msopa; ORFNames=CG14560;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC TISSUE=Abdomen;
RX PubMed=1883837; DOI=10.1016/0167-4781(91)90045-n;
RA Grabowski D.T., Carney J.P., Kelley M.R.;
RT "An adult male specific gene in Drosophila containing the repetitive
RT element opa.";
RL Biochim. Biophys. Acta 1090:115-118(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC TISSUE=Abdomen;
RX PubMed=1674131; DOI=10.1093/nar/19.7.1709;
RA Grabowski D.T., Carney J.P., Kelley M.R.;
RT "A Drosophila gene containing the opa repetitive element is exclusively
RT expressed in adult male abdomens.";
RL Nucleic Acids Res. 19:1709-1709(1991).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
CC -!- FUNCTION: May be a male specific regulatory factor.
CC -!- TISSUE SPECIFICITY: Adult male abdomen. {ECO:0000269|PubMed:1674131,
CC ECO:0000269|PubMed:1883837}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA39846.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X56491; CAA39846.1; ALT_FRAME; mRNA.
DR EMBL; AE014296; AAF51808.1; -; Genomic_DNA.
DR RefSeq; NP_001262203.1; NM_001275274.1.
DR RefSeq; NP_524859.2; NM_080120.3.
DR AlphaFoldDB; P23488; -.
DR STRING; 7227.FBpp0306233; -.
DR PaxDb; P23488; -.
DR DNASU; 45962; -.
DR EnsemblMetazoa; FBtr0078482; FBpp0078135; FBgn0004414.
DR EnsemblMetazoa; FBtr0334114; FBpp0306233; FBgn0004414.
DR GeneID; 45962; -.
DR KEGG; dme:Dmel_CG14560; -.
DR CTD; 45962; -.
DR FlyBase; FBgn0004414; msopa.
DR VEuPathDB; VectorBase:FBgn0004414; -.
DR HOGENOM; CLU_205495_0_0_1; -.
DR OMA; KKNVNHN; -.
DR BioGRID-ORCS; 45962; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 45962; -.
DR PRO; PR:P23488; -.
DR Proteomes; UP000000803; Chromosome 3L.
DR Bgee; FBgn0004414; Expressed in male reproductive gland and 8 other tissues.
DR ExpressionAtlas; P23488; differential.
DR Genevisible; P23488; DM.
DR GO; GO:0005615; C:extracellular space; HDA:FlyBase.
DR GO; GO:0006952; P:defense response; ISS:FlyBase.
DR GO; GO:0019953; P:sexual reproduction; HEP:FlyBase.
PE 2: Evidence at transcript level;
KW Reference proteome; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..83
FT /note="Male-specific opa-containing protein"
FT /id="PRO_0000021916"
FT REGION 23..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..61
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 44
FT /note="P -> A (in Ref. 1)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 83 AA; 7938 MW; 100ADE6687380FC3 CRC64;
MNFIQIAVLF VLVAVALARP QEDPANLPAP EAAAAPPAAA AAPPAAAAAP PAPPAPPAAA
PQAAPAGGSG RKKNVNHNVI TIG
