OPF15_ARATH
ID OPF15_ARATH Reviewed; 261 AA.
AC Q9SJ45; Q8GX20;
DT 09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Transcription repressor OFP15;
DE AltName: Full=Ovate family protein 15;
DE Short=AtOFP15;
GN Name=OFP15; OrderedLocusNames=At2g36050; ORFNames=F11F19.32;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP INTERACTION WITH BLH1 AND BLH3.
RX PubMed=15781858; DOI=10.1073/pnas.0501181102;
RA Hackbusch J., Richter K., Muller J., Salamini F., Uhrig J.F.;
RT "A central role of Arabidopsis thaliana ovate family proteins in networking
RT and subcellular localization of 3-aa loop extension homeodomain proteins.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:4908-4912(2005).
RN [6]
RP FUNCTION, TISSUE SPECIFICITY, GENE FAMILY, AND DISRUPTION PHENOTYPE.
RX PubMed=21886836; DOI=10.1371/journal.pone.0023896;
RA Wang S., Chang Y., Guo J., Zeng Q., Ellis B.E., Chen J.G.;
RT "Arabidopsis ovate family proteins, a novel transcriptional repressor
RT family, control multiple aspects of plant growth and development.";
RL PLoS ONE 6:E23896-E23896(2011).
CC -!- FUNCTION: Transcriptional repressor that regulates multiple aspects of
CC plant growth and development through the regulation of BEL1-LIKE (BLH)
CC and KNOX TALE (KNAT) homeodomain transcription factors.
CC {ECO:0000269|PubMed:21886836}.
CC -!- SUBUNIT: Interacts with BLH1 and BLH3. {ECO:0000269|PubMed:15781858}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, cauline leaves, shoots, flower
CC buds and siliques. {ECO:0000269|PubMed:21886836}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:21886836}.
CC -!- MISCELLANEOUS: Plants over-expressing OFP15 show small rosette size,
CC late flowering, reduced fertilization and blunt-end siliques.
CC {ECO:0000305|PubMed:21886836}.
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DR EMBL; AC007017; AAD21452.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09197.1; -; Genomic_DNA.
DR EMBL; AK118491; BAC43095.1; -; mRNA.
DR EMBL; AY044326; AAK73267.1; -; mRNA.
DR PIR; C84776; C84776.
DR RefSeq; NP_565833.1; NM_129164.3.
DR AlphaFoldDB; Q9SJ45; -.
DR BioGRID; 3522; 3.
DR IntAct; Q9SJ45; 3.
DR STRING; 3702.AT2G36050.1; -.
DR PaxDb; Q9SJ45; -.
DR PRIDE; Q9SJ45; -.
DR EnsemblPlants; AT2G36050.1; AT2G36050.1; AT2G36050.
DR GeneID; 818178; -.
DR Gramene; AT2G36050.1; AT2G36050.1; AT2G36050.
DR KEGG; ath:AT2G36050; -.
DR Araport; AT2G36050; -.
DR TAIR; locus:2039290; AT2G36050.
DR eggNOG; ENOG502RFQ4; Eukaryota.
DR HOGENOM; CLU_066339_1_0_1; -.
DR InParanoid; Q9SJ45; -.
DR OMA; STDNCIT; -.
DR OrthoDB; 1441585at2759; -.
DR PhylomeDB; Q9SJ45; -.
DR PRO; PR:Q9SJ45; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SJ45; baseline and differential.
DR Genevisible; Q9SJ45; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR InterPro; IPR038933; Ovate.
DR InterPro; IPR006458; Ovate_C.
DR PANTHER; PTHR33057; PTHR33057; 1.
DR Pfam; PF04844; Ovate; 1.
DR TIGRFAMs; TIGR01568; A_thal_3678; 1.
DR PROSITE; PS51754; OVATE; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..261
FT /note="Transcription repressor OFP15"
FT /id="PRO_0000429684"
FT DOMAIN 112..172
FT /note="OVATE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01090"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 54
FT /note="D -> G (in Ref. 3; BAC43095)"
FT /evidence="ECO:0000305"
FT CONFLICT 176
FT /note="D -> G (in Ref. 3; BAC43095)"
FT /evidence="ECO:0000305"
FT CONFLICT 219
FT /note="S -> F (in Ref. 3; BAC43095)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 261 AA; 29068 MW; 2D437F4D763B617B CRC64;
MKLPFLNKNH STSSYSSNSS SSSWPWPSCN QNPKTLSFRA TITFTNPIHD QDDDELDLLD
PPEITDSVEN VIKGLRSSER LIFESKGETN SILEEATSKR EEEDEEEGFM LFSLESDDPY
SDFKRSMEEM VEAHALHHDW KSLEKLLLQF LKVNAKTSHR YIFAAFVDLL MNLALDTKKA
IINNDISKDD GVSASRAAAA GEASTSCCNS MTLGESPSSP LSFYTSCSSS SSSDETSSMS
VRFLPLSSLL EMDEKTKEIL V
