ID   OPGC_ECOBW              Reviewed;         385 AA.
AC   C4ZRY8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Glucans biosynthesis protein C {ECO:0000255|HAMAP-Rule:MF_01066};
DE            EC=2.1.-.- {ECO:0000255|HAMAP-Rule:MF_01066};
GN   Name=mdoC {ECO:0000255|HAMAP-Rule:MF_01066};
GN   Synonyms=opgC {ECO:0000255|HAMAP-Rule:MF_01066};
GN   OrderedLocusNames=BWG_0896;
OS   Escherichia coli (strain K12 / MC4100 / BW2952).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=595496;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MC4100 / BW2952;
RX   PubMed=19376874; DOI=10.1128/jb.00118-09;
RA   Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R.,
RA   Wang L.;
RT   "Genomic sequencing reveals regulatory mutations and recombinational events
RT   in the widely used MC4100 lineage of Escherichia coli K-12.";
RL   J. Bacteriol. 191:4025-4029(2009).
CC   -!- FUNCTION: Necessary for the succinyl substitution of periplasmic
CC       glucans. Could catalyze the transfer of succinyl residues from the
CC       cytoplasmic side of the membrane to the nascent glucan backbones on the
CC       periplasmic side of the membrane. {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01066};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- SIMILARITY: Belongs to the acyltransferase 3 family. OpgC subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001396; ACR63741.1; -; Genomic_DNA.
DR   RefSeq; WP_001070375.1; NC_012759.1.
DR   AlphaFoldDB; C4ZRY8; -.
DR   KEGG; ebw:BWG_0896; -.
DR   HOGENOM; CLU_036182_2_0_6; -.
DR   OMA; YFSYMLY; -.
DR   UniPathway; UPA00637; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0016741; F:transferase activity, transferring one-carbon groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01066; MdoC_OpgC; 1.
DR   InterPro; IPR002656; Acyl_transf_3_dom.
DR   InterPro; IPR023723; Glucans_biosynth_C.
DR   Pfam; PF01757; Acyl_transf_3; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Cell membrane; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..385
FT                   /note="Glucans biosynthesis protein C"
FT                   /id="PRO_1000213465"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
SQ   SEQUENCE   385 AA;  44690 MW;  24B869CE8E0224DF CRC64;
     MNPVPAQREY FLDSIRAWLM LLGIPFHISL IYSSHTWHVN SAESSLWLTL FNDFIHSFRM
     QVFFVISGYF SYMLFLRYPL KKWWKVRVER VGIPMLTAIP LLTLPQFIML QYVKGKAESW
     PGLSLYDKYN TLAWELISHL WFLLVLVVMT TLCVWIFKRI RNNLENSDKT NKKFSMVKLS
     VIFLCLGIGY AVIRRTIFIV YPPILSNGMF NFIVMQTLFY LPFFILGALA FIFPHLKALF
     TTPSRGCTLA AALAFVAYLL NQRYGSGDAW MYETESVITM VLGLWMVNVV FSFGHRLLNF
     QSARVTYFVN ASLFIYLVHH PLTLFFGAYI TPHITSNWLG FLCGLIFVVG IAIILYEIHL
     RIPLLKFLFS GKPVVKREND KAPAR