ID   OPGC_ECOL6              Reviewed;         385 AA.
AC   P67559; Q83RU4; Q8FIS5;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Glucans biosynthesis protein C {ECO:0000255|HAMAP-Rule:MF_01066};
DE            EC=2.1.-.- {ECO:0000255|HAMAP-Rule:MF_01066};
GN   Name=mdoC {ECO:0000255|HAMAP-Rule:MF_01066};
GN   Synonyms=opgC {ECO:0000255|HAMAP-Rule:MF_01066}; OrderedLocusNames=c1311;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Necessary for the succinyl substitution of periplasmic
CC       glucans. Could catalyze the transfer of succinyl residues from the
CC       cytoplasmic side of the membrane to the nascent glucan backbones on the
CC       periplasmic side of the membrane. {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01066};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- SIMILARITY: Belongs to the acyltransferase 3 family. OpgC subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01066}.
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DR   EMBL; AE014075; AAN79784.1; -; Genomic_DNA.
DR   RefSeq; WP_001070350.1; NC_004431.1.
DR   AlphaFoldDB; P67559; -.
DR   STRING; 199310.c1311; -.
DR   EnsemblBacteria; AAN79784; AAN79784; c1311.
DR   GeneID; 66670685; -.
DR   KEGG; ecc:c1311; -.
DR   eggNOG; COG1835; Bacteria.
DR   HOGENOM; CLU_036182_2_0_6; -.
DR   OMA; YFSYMLY; -.
DR   BioCyc; ECOL199310:C1311-MON; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0016741; F:transferase activity, transferring one-carbon groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01066; MdoC_OpgC; 1.
DR   InterPro; IPR002656; Acyl_transf_3_dom.
DR   InterPro; IPR023723; Glucans_biosynth_C.
DR   Pfam; PF01757; Acyl_transf_3; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Cell membrane; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..385
FT                   /note="Glucans biosynthesis protein C"
FT                   /id="PRO_0000218050"
FT   TRANSMEM        17..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        54..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        88..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        136..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        179..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        213..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        242..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        276..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        308..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        334..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
SQ   SEQUENCE   385 AA;  44700 MW;  D8459ADC7C1E653C CRC64;
     MNPVPAQREY FLDSIRAWLM LLGIPFHISL IYSSHTWHVN SAEPSLWLTL FNDFIHSFRM
     QVFFVISGYF SYMLFLRYPL KKWWKVRVER VGIPMLTAIP LLTLPQFIML QYVKGKAESW
     PGLSLYDKYN TLAWELISHL WFLLVLVVMT TLCVWIFKRI RNNLENSDKT NKKFSMVKLS
     VIFLCLGIGY AVIRRTIFIV YPPILSNGMF NFIVMQTLFY LPFFILGALA FIFPHLKALF
     TTPSRGCTLA AALAFVAYLL NQRYGSGDAW MYETESVITM VLGLWMVNVV FSFGHRLLNF
     QSARVTYFVN ASLFIYLVHH PLTLFFGAYI TPHITSNWLG FLCGLIFVVG IAIILYEIHL
     RIPLLKFLFS GKPVVKREND KAPAR