ID   OPGC_SHIF8              Reviewed;         385 AA.
AC   Q0T5Z5;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Glucans biosynthesis protein C {ECO:0000255|HAMAP-Rule:MF_01066};
DE            EC=2.1.-.- {ECO:0000255|HAMAP-Rule:MF_01066};
GN   Name=mdoC {ECO:0000255|HAMAP-Rule:MF_01066};
GN   Synonyms=opgC {ECO:0000255|HAMAP-Rule:MF_01066};
GN   OrderedLocusNames=SFV_1059;
OS   Shigella flexneri serotype 5b (strain 8401).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=373384;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8401;
RX   PubMed=16822325; DOI=10.1186/1471-2164-7-173;
RA   Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J.,
RA   Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.;
RT   "Complete genome sequence of Shigella flexneri 5b and comparison with
RT   Shigella flexneri 2a.";
RL   BMC Genomics 7:173-173(2006).
CC   -!- FUNCTION: Necessary for the succinyl substitution of periplasmic
CC       glucans. Could catalyze the transfer of succinyl residues from the
CC       cytoplasmic side of the membrane to the nascent glucan backbones on the
CC       periplasmic side of the membrane. {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01066};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01066}.
CC   -!- SIMILARITY: Belongs to the acyltransferase 3 family. OpgC subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01066}.
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DR   EMBL; CP000266; ABF03270.1; -; Genomic_DNA.
DR   RefSeq; WP_001070350.1; NC_008258.1.
DR   AlphaFoldDB; Q0T5Z5; -.
DR   EnsemblBacteria; ABF03270; ABF03270; SFV_1059.
DR   GeneID; 66670685; -.
DR   KEGG; sfv:SFV_1059; -.
DR   HOGENOM; CLU_036182_2_0_6; -.
DR   OMA; YFSYMLY; -.
DR   BioCyc; SFLE373384:SFV_RS05850-MON; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000000659; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0016741; F:transferase activity, transferring one-carbon groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01066; MdoC_OpgC; 1.
DR   InterPro; IPR002656; Acyl_transf_3_dom.
DR   InterPro; IPR023723; Glucans_biosynth_C.
DR   Pfam; PF01757; Acyl_transf_3; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Cell membrane; Membrane; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..385
FT                   /note="Glucans biosynthesis protein C"
FT                   /id="PRO_1000064517"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01066"
SQ   SEQUENCE   385 AA;  44700 MW;  D8459ADC7C1E653C CRC64;
     MNPVPAQREY FLDSIRAWLM LLGIPFHISL IYSSHTWHVN SAEPSLWLTL FNDFIHSFRM
     QVFFVISGYF SYMLFLRYPL KKWWKVRVER VGIPMLTAIP LLTLPQFIML QYVKGKAESW
     PGLSLYDKYN TLAWELISHL WFLLVLVVMT TLCVWIFKRI RNNLENSDKT NKKFSMVKLS
     VIFLCLGIGY AVIRRTIFIV YPPILSNGMF NFIVMQTLFY LPFFILGALA FIFPHLKALF
     TTPSRGCTLA AALAFVAYLL NQRYGSGDAW MYETESVITM VLGLWMVNVV FSFGHRLLNF
     QSARVTYFVN ASLFIYLVHH PLTLFFGAYI TPHITSNWLG FLCGLIFVVG IAIILYEIHL
     RIPLLKFLFS GKPVVKREND KAPAR