OPGD_SALPK
ID OPGD_SALPK Reviewed; 551 AA.
AC B5BJ86;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Glucans biosynthesis protein D {ECO:0000255|HAMAP-Rule:MF_01068};
DE Flags: Precursor;
GN Name=mdoD {ECO:0000255|HAMAP-Rule:MF_01068};
GN Synonyms=opgD {ECO:0000255|HAMAP-Rule:MF_01068};
GN OrderedLocusNames=SSPA1156;
OS Salmonella paratyphi A (strain AKU_12601).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=554290;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AKU_12601;
RX PubMed=19159446; DOI=10.1186/1471-2164-10-36;
RA Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hasan R., Bhutta Z.A.,
RA Quail M.A., Norbertczak H., Walker D., Simmonds M., White B., Bason N.,
RA Mungall K., Dougan G., Parkhill J.;
RT "Pseudogene accumulation in the evolutionary histories of Salmonella
RT enterica serovars Paratyphi A and Typhi.";
RL BMC Genomics 10:36-36(2009).
CC -!- FUNCTION: Probably involved in the control of the structural glucose
CC backbone of osmoregulated periplasmic glucans (OPGs).
CC {ECO:0000255|HAMAP-Rule:MF_01068}.
CC -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01068}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000255|HAMAP-Rule:MF_01068}.
CC -!- PTM: Predicted to be exported by the Tat system. The position of the
CC signal peptide cleavage has not been experimentally proven.
CC -!- SIMILARITY: Belongs to the OpgD/OpgG family. {ECO:0000255|HAMAP-
CC Rule:MF_01068}.
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DR EMBL; FM200053; CAR59318.1; -; Genomic_DNA.
DR RefSeq; WP_001081950.1; NC_011147.1.
DR AlphaFoldDB; B5BJ86; -.
DR SMR; B5BJ86; -.
DR PRIDE; B5BJ86; -.
DR KEGG; sek:SSPA1156; -.
DR HOGENOM; CLU_023403_2_0_6; -.
DR OMA; DVQFFHV; -.
DR UniPathway; UPA00637; -.
DR Proteomes; UP000001869; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.40.10; -; 1.
DR Gene3D; 2.70.98.10; -; 1.
DR HAMAP; MF_01068; MdoD_OpgD; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR023724; Glucan_biosyn_MdoD.
DR InterPro; IPR014438; Glucan_biosyn_MdoG/MdoD.
DR InterPro; IPR007444; Glucan_biosyn_MdoG_C.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR006311; TAT_signal.
DR InterPro; IPR019546; TAT_signal_bac_arc.
DR PANTHER; PTHR30504; PTHR30504; 1.
DR Pfam; PF04349; MdoG; 1.
DR PIRSF; PIRSF006281; MdoG; 1.
DR SUPFAM; SSF74650; SSF74650; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
DR TIGRFAMs; TIGR01409; TAT_signal_seq; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Periplasm; Signal.
FT SIGNAL 1..32
FT /note="Tat-type signal"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01068"
FT CHAIN 33..551
FT /note="Glucans biosynthesis protein D"
FT /id="PRO_1000136602"
SQ SEQUENCE 551 AA; 62316 MW; C30DECB3AC33D76A CRC64;
MNRRRFIKGS MAMAAVCGSS GIASLFSQAA FAAESDIADG KIVRFDFAGL QSMAQALAKK
PWGGAPGPLP DTLANLTPQA YNSIQYDAAH SLWNGVANRQ LDIQFFHVGM GFRRRVRMFS
VDTTTHLARE IHFRPELFKY NDAGVDTTQL EGQSDLGFAG FRVFKAPELA RRDVVSFLGA
SYFRAVDDTY QYGLSARGLA IDTYTDGQEE FPDFTAFWFD TAKPGDTTFT VYALLDSASV
TGAYKFVIHC EKTQVIMDVE NHLYARKDIK QLGIAPMTSM FSCGNNERRV CDTIHPQIHD
SDRLAMWRGN GEWICRPLNN PQKLQFNAYM DDNPKGFGLL QLDRDFSHYQ DVMDWYNKRP
SLWVEPRSKW GKGAVSLMEI PTTGETLDNV VCFWQPEKAI KAGDTLVFNY RLYWSAQPPV
QSPLARVMAT RTGMGGFPEG WAPGEHYPDK WARRFAIDFV GGDLKAAAPK SIEPVITLSS
GEAKQVEILY VEPFDGYRIQ FDWYPTSDST APVDMRMFLR CQGEAISETW LYQYFPPAPD
KRRYVDDRIM R