ID   OPGD_SALTI              Reviewed;         551 AA.
AC   Q8Z765;
DT   03-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   03-JUL-2003, sequence version 2.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Glucans biosynthesis protein D;
DE   Flags: Precursor;
GN   Name=mdoD; Synonyms=opgD; OrderedLocusNames=STY1442, t1531;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Probably involved in the control of the structural glucose
CC       backbone of osmoregulated periplasmic glucans (OPGs). {ECO:0000250}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- PTM: Predicted to be exported by the Tat system. The position of the
CC       signal peptide cleavage has not been experimentally proven.
CC   -!- SIMILARITY: Belongs to the OpgD/OpgG family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO69166.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAD01703.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL513382; CAD01703.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE014613; AAO69166.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_455875.1; NC_003198.1.
DR   RefSeq; WP_001081955.1; NZ_WSUR01000020.1.
DR   AlphaFoldDB; Q8Z765; -.
DR   SMR; Q8Z765; -.
DR   STRING; 220341.16502553; -.
DR   EnsemblBacteria; AAO69166; AAO69166; t1531.
DR   KEGG; stt:t1531; -.
DR   KEGG; sty:STY1442; -.
DR   PATRIC; fig|220341.7.peg.1452; -.
DR   eggNOG; COG3131; Bacteria.
DR   HOGENOM; CLU_023403_2_0_6; -.
DR   OMA; DVQFFHV; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.40.10; -; 1.
DR   Gene3D; 2.70.98.10; -; 1.
DR   HAMAP; MF_01068; MdoD_OpgD; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR023724; Glucan_biosyn_MdoD.
DR   InterPro; IPR014438; Glucan_biosyn_MdoG/MdoD.
DR   InterPro; IPR007444; Glucan_biosyn_MdoG_C.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR006311; TAT_signal.
DR   InterPro; IPR019546; TAT_signal_bac_arc.
DR   PANTHER; PTHR30504; PTHR30504; 1.
DR   Pfam; PF04349; MdoG; 1.
DR   PIRSF; PIRSF006281; MdoG; 1.
DR   SUPFAM; SSF74650; SSF74650; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   TIGRFAMs; TIGR01409; TAT_signal_seq; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..32
FT                   /note="Tat-type signal"
FT                   /evidence="ECO:0000255"
FT   CHAIN           33..551
FT                   /note="Glucans biosynthesis protein D"
FT                   /id="PRO_0000020212"
SQ   SEQUENCE   551 AA;  62199 MW;  B0F7E8813FE7120C CRC64;
     MNRRRFIKGS MAMAAVCGSS GIASLFSQAA FAAESDIADG KIVRFDFAGL QSMAQALAKK
     PWGGAPGPLP DTLANLTPQA YNSIQYDAAH SLWNGVANRQ LDIQFFHVGM GFRRRVRMFS
     VDTTTHLARE IHFRPELFKY NDAGVDTTQL EGQSDLGFAG FRVFKAPELA RRDVVSFLGA
     SYFRAVDDTY QYGLSARGLA IDTYTDGQEE FPDFTAFWFD TAKPGDTTFT VYALLDSASV
     TGAYKFVIHC EKTQVIMDVE NHLYARKDIK QLGIAPMTSM FSCGNNERRV CDTIHPQIHD
     SDRLAMWRGN GEWICRPLNN PQKLQFNAYM DDNPKGFGLL QLDRDFSHYQ DVMGWYNKRP
     SLWVEPRSKW GKGAVSLMEI PTTGETLDNV VCFWQPEKAI KAGDTLAFNY RLYWSAQPPV
     QSPLARVMAT RTGMGGFPEG WAPGEHYPDK WARRFAIDFV GGDLKAAAPK GIEPVITLSS
     GEAKQVEILY VEPFDGYRIQ FDWYPTSDST APVDMRMFLR CQGEAISETW LYQYFPPAPD
     KRRYVDDRIM R