ARY1_CHICK
ID ARY1_CHICK Reviewed; 290 AA.
AC P13913;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1990, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Arylamine N-acetyltransferase, pineal gland isozyme NAT-10;
DE Short=Arylamine acetylase;
DE EC=2.3.1.5;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=White leghorn; TISSUE=Pineal gland;
RX PubMed=2583181; DOI=10.1111/j.1432-1033.1989.tb15110.x;
RA Ohtomi M., Sasaki M., Deguchi T.;
RT "Two arylamine N-acetyltransferases from chicken pineal gland as identified
RT by cDNA cloning.";
RL Eur. J. Biochem. 185:253-261(1989).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + an arylamine = an N-acetylarylamine + CoA;
CC Xref=Rhea:RHEA:16613, ChEBI:CHEBI:13790, ChEBI:CHEBI:50471,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.5;
CC -!- SIMILARITY: Belongs to the arylamine N-acetyltransferase family.
CC {ECO:0000305}.
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DR EMBL; X16021; CAA34153.1; -; mRNA.
DR PIR; S06653; XYCHY0.
DR RefSeq; NP_990671.1; NM_205340.1.
DR AlphaFoldDB; P13913; -.
DR SMR; P13913; -.
DR STRING; 9031.ENSGALP00000008780; -.
DR PaxDb; P13913; -.
DR GeneID; 396283; -.
DR KEGG; gga:396283; -.
DR CTD; 396283; -.
DR VEuPathDB; HostDB:geneid_396283; -.
DR eggNOG; ENOG502RD0D; Eukaryota.
DR OrthoDB; 1545569at2759; -.
DR PhylomeDB; P13913; -.
DR PRO; PR:P13913; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0004060; F:arylamine N-acetyltransferase activity; IBA:GO_Central.
DR InterPro; IPR001447; Arylamine_N-AcTrfase.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR11786; PTHR11786; 1.
DR Pfam; PF00797; Acetyltransf_2; 1.
DR PRINTS; PR01543; ANATRNSFRASE.
DR SUPFAM; SSF54001; SSF54001; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase; Reference proteome; Transferase.
FT CHAIN 1..290
FT /note="Arylamine N-acetyltransferase, pineal gland isozyme
FT NAT-10"
FT /id="PRO_0000107901"
FT ACT_SITE 68
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000250"
FT ACT_SITE 107
FT /evidence="ECO:0000250"
FT ACT_SITE 122
FT /evidence="ECO:0000250"
SQ SEQUENCE 290 AA; 33925 MW; CBED93184E5F137C CRC64;
MNLEEYFART GYKGSLENQD LETLTDIFQH HIRAVPFENL SIHCGEKITL ELEHVYNKIV
HKKRGGWCME NNQLLGWVLK CLGYDTSFLG AYVFNPHENA YATIMTHLLV KVVIEGKAYI
VDAGFGVSYQ MWQPMELVSG KDQPQAPGIF RFTEKNAIWY LEKMRRKQYI PNQNFSNSDL
LEKKDCRKVY MFSLEPRTVE DFCFQCTYLQ TSPDSLFTKK SICTLQTTDG FRALIGWTLT
ETKYNYKENM DLVEFITLKD EEVEKTLKDK FNITLERKLV PINVKGFYTI