OPGG_SHIFL
ID OPGG_SHIFL Reviewed; 511 AA.
AC Q83RU3;
DT 03-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 03-JUL-2003, sequence version 2.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Glucans biosynthesis protein G;
DE Flags: Precursor;
GN Name=mdoG; Synonyms=opgG; OrderedLocusNames=SF1044, S1118;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC glucans (OPGs). {ECO:0000250}.
CC -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC biosynthesis.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OpgD/OpgG family. {ECO:0000305}.
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DR EMBL; AE005674; AAN42666.2; -; Genomic_DNA.
DR EMBL; AE014073; AAP16550.1; -; Genomic_DNA.
DR RefSeq; NP_706959.2; NC_004337.2.
DR RefSeq; WP_011069327.1; NZ_WPGW01000143.1.
DR AlphaFoldDB; Q83RU3; -.
DR SMR; Q83RU3; -.
DR STRING; 198214.SF1044; -.
DR EnsemblBacteria; AAN42666; AAN42666; SF1044.
DR EnsemblBacteria; AAP16550; AAP16550; S1118.
DR GeneID; 1023993; -.
DR KEGG; sfl:SF1044; -.
DR KEGG; sfx:S1118; -.
DR PATRIC; fig|198214.7.peg.1218; -.
DR HOGENOM; CLU_023403_2_0_6; -.
DR OMA; KRPSAWI; -.
DR UniPathway; UPA00637; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.40.10; -; 1.
DR Gene3D; 2.70.98.10; -; 1.
DR HAMAP; MF_01069; MdoG_OpgG; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR014438; Glucan_biosyn_MdoG/MdoD.
DR InterPro; IPR007444; Glucan_biosyn_MdoG_C.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR023704; MdoG_OpgG.
DR PANTHER; PTHR30504; PTHR30504; 1.
DR Pfam; PF04349; MdoG; 1.
DR PIRSF; PIRSF006281; MdoG; 1.
DR SUPFAM; SSF74650; SSF74650; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
PE 3: Inferred from homology;
KW Periplasm; Reference proteome; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..511
FT /note="Glucans biosynthesis protein G"
FT /id="PRO_0000020236"
SQ SEQUENCE 511 AA; 57923 MW; 74C4138CD57AFBC4 CRC64;
MMKMRWLSAA VMLTLYTSSS WAFSIDDVAK QAQSLAGKGY EAPKSNLPSV FRDMKYADYQ
QIQFNHDKAY WNNLKTPFKL EFYHQGMYFD TPVKINEVTA TAVKRIKYSP DYFTFGDVQH
DKDTVKDLGF AGFKVLYPIN SKDKNDEIVS MLGASYFRVI GAGQVYGLSA RGLAIDTALP
SGEEFPRFKE FWIERPKPTD KRLTIYALLD SPRATGAYKF VVMPGRDTVV DVQSKIYLRD
KVGKLGVAPL TSMFLFGPNQ PSPANNYRPE LHDSNGLSIH AGNGEWIWRP LNNPKHLAVS
SFSMENPRGF GLLQRGRDFS RFEDLDDRYD LRPSAWVTPK GEWGKGSVEL VEIPTNDETN
DNIVAYWTPD QLPEPGKEMN FKYTITFSRD EDKLHAPDNA WVQQTRRSTG DVKQSNLIRQ
PDGTIAFVVD FTGAEMKKLP EDTPVTAQTS IGDNGEIVES TVRYNPVTKG WRLVMRVKVK
DAKKITEMRA ALVNADQTLS ETWSYQLPAN E