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OPGH_CAUVC
ID   OPGH_CAUVC              Reviewed;         663 AA.
AC   Q9A6R5;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; OrderedLocusNames=CC_2018;
OS   Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA   Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA   Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA   Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA   Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; AE005673; AAK23993.1; -; Genomic_DNA.
DR   PIR; E87499; E87499.
DR   RefSeq; NP_420825.1; NC_002696.2.
DR   RefSeq; WP_010919884.1; NC_002696.2.
DR   AlphaFoldDB; Q9A6R5; -.
DR   STRING; 190650.CC_2018; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   EnsemblBacteria; AAK23993; AAK23993; CC_2018.
DR   KEGG; ccr:CC_2018; -.
DR   PATRIC; fig|190650.5.peg.2038; -.
DR   eggNOG; COG2943; Bacteria.
DR   HOGENOM; CLU_015730_1_0_5; -.
DR   OMA; TAGLHYW; -.
DR   BioCyc; CAULO:CC2018-MON; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000001816; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF13632; Glyco_trans_2_3; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..663
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_0000210348"
FT   TRANSMEM        64..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        101..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        413..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        470..492
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        558..580
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        584..606
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
SQ   SEQUENCE   663 AA;  72443 MW;  A57C91277B09CD96 CRC64;
     MSDRSSLFDV RSSTSVTLDQ VVRRDTVEIP DEAALAMPVQ PLSFWQGGAR RATALTQDMN
     LRRWMLGLMT IAMGVAGWKA SFDTIALGGV TRLEAVVLTL LAPLFLALSL WFCTALIGFV
     VLMGRPKDPL GIDSEAPMPK LHTRTAILMP VYNEDAAAVF ARLRAMDASI AETGSARNFD
     IFVISDTRDA QVALAEQACF ARFRREANCN VYYRIRKENT GRKAGNVADW VSRWGSAYEH
     MLVLDADSLM TGEAMVRLAD AMERHPGAGL IQTMPMIING QTIFARTLQF ATRLYGRVAW
     TGLAWWSGSE SSFWGHNAIV RTRAFAETCG LPHLPGPKPF GGEVMSHDAL ESALLRRGGW
     SVHLAPYLDG SYEESPSNLL DFATRDRRWC RGNIQHVPLI ALPGLHWMSR MHLVIGVLSY
     ALSPLWFFCL SAGLISRALM PELKKAAFTM ADLKAAAHAL IDWSEIQATA WAMIITFVLL
     FGPKILGAIL VLARKGEVKG FGGKRRMAAG LGVEMLLSAL VAPMLMFTQT RAIVEILAGK
     VGGWAAQRRD ADKVDFKEAW AAMGWISLSG LILAASFWFT PDLLTATAPI LAGLVLAVPL
     TMLGAHKVAG LKLKANGLFM TPEERRPPAI VRAAVGAACE PPIRWFARNG RPIGPTTKIR
     DAA
 
 
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