OPGH_CAUVN
ID OPGH_CAUVN Reviewed; 663 AA.
AC B8GX72;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; OrderedLocusNames=CCNA_02097;
OS Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=565050;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA1000 / CB15N;
RX PubMed=20472802; DOI=10.1128/jb.00255-10;
RA Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA Walunas T.L., Crosson S.;
RT "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL J. Bacteriol. 192:3678-3688(2010).
CC -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01072}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR EMBL; CP001340; ACL95562.1; -; Genomic_DNA.
DR RefSeq; WP_010919884.1; NC_011916.1.
DR RefSeq; YP_002517470.1; NC_011916.1.
DR AlphaFoldDB; B8GX72; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PRIDE; B8GX72; -.
DR EnsemblBacteria; ACL95562; ACL95562; CCNA_02097.
DR GeneID; 7330403; -.
DR KEGG; ccs:CCNA_02097; -.
DR PATRIC; fig|565050.3.peg.2056; -.
DR HOGENOM; CLU_015730_1_0_5; -.
DR OMA; TAGLHYW; -.
DR OrthoDB; 1049243at2; -.
DR PhylomeDB; B8GX72; -.
DR UniPathway; UPA00637; -.
DR Proteomes; UP000001364; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.550.10; -; 1.
DR HAMAP; MF_01072; MdoH_OpgH; 1.
DR InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..663
FT /note="Glucans biosynthesis glucosyltransferase H"
FT /id="PRO_1000149760"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 415..435
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 507..527
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 559..579
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 583..603
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
SQ SEQUENCE 663 AA; 72443 MW; A57C91277B09CD96 CRC64;
MSDRSSLFDV RSSTSVTLDQ VVRRDTVEIP DEAALAMPVQ PLSFWQGGAR RATALTQDMN
LRRWMLGLMT IAMGVAGWKA SFDTIALGGV TRLEAVVLTL LAPLFLALSL WFCTALIGFV
VLMGRPKDPL GIDSEAPMPK LHTRTAILMP VYNEDAAAVF ARLRAMDASI AETGSARNFD
IFVISDTRDA QVALAEQACF ARFRREANCN VYYRIRKENT GRKAGNVADW VSRWGSAYEH
MLVLDADSLM TGEAMVRLAD AMERHPGAGL IQTMPMIING QTIFARTLQF ATRLYGRVAW
TGLAWWSGSE SSFWGHNAIV RTRAFAETCG LPHLPGPKPF GGEVMSHDAL ESALLRRGGW
SVHLAPYLDG SYEESPSNLL DFATRDRRWC RGNIQHVPLI ALPGLHWMSR MHLVIGVLSY
ALSPLWFFCL SAGLISRALM PELKKAAFTM ADLKAAAHAL IDWSEIQATA WAMIITFVLL
FGPKILGAIL VLARKGEVKG FGGKRRMAAG LGVEMLLSAL VAPMLMFTQT RAIVEILAGK
VGGWAAQRRD ADKVDFKEAW AAMGWISLSG LILAASFWFT PDLLTATAPI LAGLVLAVPL
TMLGAHKVAG LKLKANGLFM TPEERRPPAI VRAAVGAACE PPIRWFARNG RPIGPTTKIR
DAA