ID   OPGH_CITK8              Reviewed;         842 AA.
AC   A8AI31;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=mdoH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Synonyms=opgH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   OrderedLocusNames=CKO_02018;
OS   Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Citrobacter.
OX   NCBI_TaxID=290338;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696;
RG   The Citrobacter koseri Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; CP000822; ABV13144.1; -; Genomic_DNA.
DR   RefSeq; WP_012132880.1; NC_009792.1.
DR   AlphaFoldDB; A8AI31; -.
DR   STRING; 290338.CKO_02018; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   EnsemblBacteria; ABV13144; ABV13144; CKO_02018.
DR   GeneID; 45135982; -.
DR   KEGG; cko:CKO_02018; -.
DR   HOGENOM; CLU_015730_1_0_6; -.
DR   OMA; TAGLHYW; -.
DR   OrthoDB; 1049243at2; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000008148; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..842
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_1000064601"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        513..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        570..590
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        615..635
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        656..676
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        680..700
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
SQ   SEQUENCE   842 AA;  96453 MW;  59088A4204105429 CRC64;
     MNKTTEYIDA MPLSDIEKAA LPKTDIRAVH EALDVEHRAY SREDDSPQGS VKARLEQAWP
     DSLAEGQLIK DNEGRDQLQA MPKATRSSMF PDPWRTNPLG RFWDRLRGRD VTPRYLSRLT
     KEEQENEQKW RTVGTIRRYI LLLLTLAQTV VATWYMKTIL PYQGWALINP ADMIGQDLWV
     SFMQLLPYVL QTGILILFAV LFCWVSAGFW TALMGFLQLL IGRDKYSISA STVGNEPLNP
     EHRTALIMPI CNEDVDRVFA GLRATWESVK ATGNAAHFDV YILSDSYNPD ICVAEQKAWM
     ELIAEVQGEG QIFYRRRRRR VKRKSGNIDD FCRRWGNQYS YMVVLDADSV MTGECLSGLV
     RLMEANPNAG IIQSSPKASG MDTLYARCQQ FATRVYGPLF TAGLHFWQLG ESHYWGHNAI
     IRVKPFIEHC ALAPLPGEGS FAGSILSHDF VEAALMRRAG WGVWIAYDLP GSYEELPPNL
     LDELKRDRRW CHGNLMNFRL FLVKGMHPVH RAVFLTGVMS YLSAPLWFMF LALSTALQVV
     HALTEPQYFL QPRQLFPVWP QWRPELAIAL FASTMVLLFL PKLLSIMLIW CKGTKEYGGF
     VRVTLSLLLE VLFSVLLAPV RMLFHTVFVV SAFLGWEVVW NSPQRDDDST PWGEAFMRHG
     SQLLLGLVWA VGMAWLDLRF LFWLAPIVFS LILSPFVSVV SSRSTVGLRT KRWKLFLIPE
     EYSPPQVLVD TDKYLAMNRN RTLDDGFMHA VFNPSFNALA TAMATARHRA SKVLEIARDR
     HVEQALNETP EKLNRDRRLV LLSDPVTMAR LHYRVWNSPE RYSSWVNYYQ GINLNPLALQ
     KK