ID   OPGH_ENT38              Reviewed;         842 AA.
AC   A4W964;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=mdoH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Synonyms=opgH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   OrderedLocusNames=Ent638_1565;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; CP000653; ABP60244.1; -; Genomic_DNA.
DR   RefSeq; WP_012016961.1; NC_009436.1.
DR   AlphaFoldDB; A4W964; -.
DR   STRING; 399742.Ent638_1565; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   EnsemblBacteria; ABP60244; ABP60244; Ent638_1565.
DR   KEGG; ent:Ent638_1565; -.
DR   eggNOG; COG2943; Bacteria.
DR   HOGENOM; CLU_015730_1_0_6; -.
DR   OMA; TAGLHYW; -.
DR   OrthoDB; 1049243at2; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..842
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_1000064602"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        513..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        570..590
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        615..635
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        680..700
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
SQ   SEQUENCE   842 AA;  96159 MW;  000EA1D08054D1B4 CRC64;
     MNNTTEYIDA LPLTDIEKAA LPKSDIRAVH TALDGEHHPF SRDDDTPLGS VKARLEQAWP
     DSLAEGQLIK DDEGRTQLQA MPKATRSSMF PDPWRTNPVG RFWDRLRGRE VAPRYLSRLT
     KEQQASEQKW RTVGTIRRYT LLLLTLAQTV VATWYMKTIL PYQGWALINP ADMFGQDVWV
     SFMQLLPYIL QSGILLLFAV LFCWVSAGFW TALMGFLQLL MGRDKYSISA STVGDEALNP
     EHRTALIMPI CNEDVDRVFA GLRATWESVK ATGNAAHFDV YILSDSYNPD ICVAEQKAWM
     ELIAEVQGEG QIFYRRRRRR VKRKSGNIDD FCRRWGNQYS YMVVLDADSV MTGECLTGLV
     RLMEANPNAG IIQSSPKASG MDTLYARCQQ FATRVYGPLF TAGLHFWQLG ESHYWGHNAI
     IRVQPFIEHC ALAPLPGEGS FAGSILSHDF VEAALMRRAG WGVWIAYDLP GSYEELPPNL
     LDELKRDRRW CHGNLMNFRL FLVKGMHPVH RAVFLTGVMS YLSAPLWFMF LALSTALQVV
     HALTEPQYFL QPRQLFPVWP QWRPELAIAL FASTMILLFL PKLLSIILIW CKGSKEYGGF
     CRVTLSLLLE VLFSVLLAPV RMLFHTVFVV SAFLGWEVVW NSPQRDDDST PWSEAFKRHG
     SQMLLGLVWA AGMAWLDLRF LFWLAPIVFS LILSPFVSVI SSRSTMGLRT KRWKLFLIPE
     EYSPPQVLVD TDKYLVLNRS RSLDDGFIHA VFNPSFNALA TAMATARHRA SQVLEIARDR
     HVEQALNETP EKLNRDRRLV LLSDPITMAR LHYRVWSAPE RYSSWVNYYS TIKLNPLAIK
     SK