ID   OPGH_NITEU              Reviewed;         867 AA.
AC   Q82SA8;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; Synonyms=mdoH;
GN   OrderedLocusNames=NE2438;
OS   Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC
OS   14298).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=228410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298;
RX   PubMed=12700255; DOI=10.1128/jb.185.9.2759-2773.2003;
RA   Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L.,
RA   Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A.,
RA   Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.;
RT   "Complete genome sequence of the ammonia-oxidizing bacterium and obligate
RT   chemolithoautotroph Nitrosomonas europaea.";
RL   J. Bacteriol. 185:2759-2773(2003).
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; AL954747; CAD86350.1; -; Genomic_DNA.
DR   RefSeq; WP_011112906.1; NC_004757.1.
DR   AlphaFoldDB; Q82SA8; -.
DR   STRING; 228410.NE2438; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   PRIDE; Q82SA8; -.
DR   EnsemblBacteria; CAD86350; CAD86350; NE2438.
DR   KEGG; neu:NE2438; -.
DR   eggNOG; COG2943; Bacteria.
DR   HOGENOM; CLU_015730_0_0_4; -.
DR   OMA; TAGLHYW; -.
DR   OrthoDB; 1049243at2; -.
DR   PhylomeDB; Q82SA8; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000001416; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..867
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_0000210353"
FT   TRANSMEM        139..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        194..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        518..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        568..590
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        603..625
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        680..702
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   REGION          71..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   867 AA;  99282 MW;  8E87B291ACAAE29C CRC64;
     MNKTTEYIDA LPLTVAEKAT LPATDIRTLH ETLNPEHHDY AREDDSPLGS VKARLEQSWP
     DSLVNRQLTE DDEGRTQLET MPKATRSSIS PDPWRTNPIG RFWDHLRGHN ATPHHVSRLT
     KEEQAHEQKW CTVGTIRRYI LLLLTFSQTA LATWYMKTIL PYQGWALIDP IDMIGQDIWI
     SFMQLLPYIL QSGILILFAI LFCWISAGFW TALMGFLQLL IGKDKYSISA SLAGDVPINP
     EHRTALIMPI CNEDVDRVFA GLRATWESVK ATNQQQHFDI YILSDSYDPD ICVAEQKAWI
     ELLAEVQDKG QIFYRRRGRR VKRKSGNIDD FCRRWGSQYS YMVVLDADSV MSGECLTSLV
     RLMEANPNAG IIQSWPRASG MDTFYARCQQ FATRVYGPLF TAGLHFWQLG ESHYWGHNAI
     IRVQPFIEHC TLALLPGEGT FAGSILSHDF VEAALMRRAG WGVWIAYDLP GSYEELPPNL
     LDELKRDRRW CHGNLMNFRL FLVKGLHPVH RAVFLTGVMS YLSAPLWFMF LALSTALQVV
     HAFTEPHYFL QPHQLFPVWP QWQPELAIAL LASTMVLLFL PKLLSILLIW CKGTKEYGGF
     IRVTISLLLE VILSVLLAPV RMLFHTVFVV SAFLGWKVAW KSPQRDDDST TWREAFMRHG
     SQLLLGLVWA TGMAWLDLRF LFWLAPIVFS LILSPFVSVF SSRASVGLRA KRWKLLLIPE
     EYSPPKVLVD TDNYLMMNRN RTLNDGFMHA VFHPSFNALT TATATARHRK SKVLEIARDH
     HIEQALNEPP DKLNRDCRLT LLSDPVIMSR LHYCVWAMPE KYASWVNHYQ QLTLNPSALK
     QCEPNIEEEA DYAEPTAQID MALPGTP