ID   OPGH_PECAS              Reviewed;         854 AA.
AC   Q6D6A7;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=mdoH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Synonyms=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; OrderedLocusNames=ECA1778;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; BX950851; CAG74683.1; -; Genomic_DNA.
DR   RefSeq; WP_011093354.1; NC_004547.2.
DR   AlphaFoldDB; Q6D6A7; -.
DR   SMR; Q6D6A7; -.
DR   STRING; 218491.ECA1778; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   EnsemblBacteria; CAG74683; CAG74683; ECA1778.
DR   KEGG; eca:ECA1778; -.
DR   PATRIC; fig|218491.5.peg.1805; -.
DR   eggNOG; COG2943; Bacteria.
DR   HOGENOM; CLU_015730_0_0_6; -.
DR   OMA; TAGLHYW; -.
DR   OrthoDB; 1049243at2; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..854
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_1000064604"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        528..548
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        583..603
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        619..639
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        671..691
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        695..715
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
SQ   SEQUENCE   854 AA;  97299 MW;  6CBCC14B0693C2A4 CRC64;
     MNKSTSSLDY IEKLPLPAEQ AEVLREKLPQ AAWNDQAVLH QALSEGSQPE GNQVNVQAED
     DVALHSVQAR LEMAWADGLD NGKQLGTDRE GRAALKAMPV ITRASMFPDV WRTNPLIRWW
     ESLLGRTVPP RPHYSPEEKI SENRWRLVGT IRRYILLALT LFQTAIATWY MKTILPYQGW
     ALIDPFEMAG QPWTRSLMQL LPYVLQSGIL VLFAVLFCWV SAGFWTALMG FLQLLIGRDK
     YSISSTTVGD EALNPEHRTA LIMPICNEDV ERVFAGLRAT YESVEATGNL EHFDIYVLSD
     SNDPDICVAE QKAWMELCRD VGGAGRIFYR RRRRRVKRKS GNIDDFCRRW GNQYSYMVIL
     DADSVMSGEC LTSLVRLMEA NPNAGIIQSS PKASGMDTLY ARCQQFATRV YGPLFTAGLH
     FWQLGESHYW GHNAIIRVKP FIEHCALAPL PGEGSFAGAI LSHDFVEAAL MRRAGWGVWI
     AYDLPGSYEE LPPNLLDELK RDRRWCHGNL MNFRLFLVKG MHPVHRAVFL TGVMSYLSAP
     LWFMFLVLST ALQVVHTLME PQYFLQPRQL FPVWPQWRPE LAIALFSTTL VLLFLPKLLS
     VILVWAKGAK EYGGAFRVFL SLLLEMLFSV LLAPVRMLFH TVFVVSAFLG WSVQWNSPQR
     DDDATPWSEA FVRHGSQLIL GLVWAIGMAW LDLRFLWWLS PIVFSLILSP VVSVYSSRAA
     LGLGCKRAKL LLIPEEFNPP RELVATDEYC RLNHQRRLDD GFMQAVFDPS VNALASAMAT
     ARHRFSRAIE DVREQNVREA LNRKPEEVSN NQRLALLSDP VTISRMHYHV WQKPEAYAAW
     VEFYQKLPAP HIKS