ID   OPGH_PECCP              Reviewed;         854 AA.
AC   C6DKV2;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=mdoH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Synonyms=opgH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   OrderedLocusNames=PC1_2522;
OS   Pectobacterium carotovorum subsp. carotovorum (strain PC1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=561230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC1;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; CP001657; ACT13553.1; -; Genomic_DNA.
DR   RefSeq; WP_015840728.1; NC_012917.1.
DR   AlphaFoldDB; C6DKV2; -.
DR   STRING; 561230.PC1_2522; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   PRIDE; C6DKV2; -.
DR   EnsemblBacteria; ACT13553; ACT13553; PC1_2522.
DR   KEGG; pct:PC1_2522; -.
DR   eggNOG; COG2943; Bacteria.
DR   HOGENOM; CLU_015730_1_0_6; -.
DR   OMA; TAGLHYW; -.
DR   OrthoDB; 1049243at2; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000002736; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..854
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_1000213476"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        528..548
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        583..603
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        619..639
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        671..691
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        695..715
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
SQ   SEQUENCE   854 AA;  97490 MW;  510A91EBC988CF21 CRC64;
     MNKSTSSLDY IEKLPLPAEQ AEVLREKLPQ AAWNDQAVLH QALSEGSPSE EHQVNVQSED
     DATLQSVQAR LEMAWAEGLD NGKQLGTDRE GRTALKAMPV ITRASMFPDV WRTNPLVRWW
     ESLLGRTVPP RPHYSPEEKI SENRWRLVGT IRRYILLVLT LFQTAIATWY MKTILPYQGW
     ALIDPFEMAG QPWTRSLMQL LPYVLQSGIL VLFAVLFCWV SAGFWTALMG FLQLLIGRDK
     YSISSTTVGN EPLNPEHRTA LIMPICNEDV ERVFAGLRAT YESVEATGNL EHFDIYVLSD
     SNDPDICVAE QKAWMELCRD VGGTGRIFYR RRRRRVKRKS GNIDDFCRRW GNQYSYMVIL
     DADSVMSGEC LTSLVRLMEA NPNAGIIQSS PKASGMDTLY ARCQQFATRV YGPLFTAGLH
     FWQLGESHYW GHNAIIRVKP FIEHCALAPL PGEGSFAGAI LSHDFVEAAL MRRAGWGVWI
     AYDLPGSYEE LPPNLLDELK RDRRWCHGNL MNFRLFLVKG MHPVHRAVFL TGVMSYLSAP
     LWFMFLMLST ALQVVHTLME PQYFLQPRQL FPVWPQWRPE LAIALFSTTL VLLFLPKLLS
     VILVWAKGAK EYGGALRVFI SLLLEMLFSV LLAPVRMLFH TVFVVSAFLG WSVQWNSPQR
     DDDATPWSEA FVRHGSQLIL GLVWAIGMAW LDLRFLWWLA PIVFSLILSP FVSVYSSRAS
     LGLGCKRAKL LMIPEEFNPP RELVATDEYC RLNHQRRLDN GFMQAVFDPS INALASAMAT
     ARHRFSQAIE DVREKNVRDA LNRKPEEVSN NQRLVLLSDP VTISRLHYHV WQKPETYAAW
     VESYQKLPAP HIKS