ID   OPGH_PSEAE              Reviewed;         861 AA.
AC   Q9HUA6;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; Synonyms=mdoH;
GN   OrderedLocusNames=PA5077;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; AE004091; AAG08462.1; -; Genomic_DNA.
DR   PIR; H83012; H83012.
DR   RefSeq; NP_253764.1; NC_002516.2.
DR   RefSeq; WP_003103448.1; NZ_QZGE01000002.1.
DR   AlphaFoldDB; Q9HUA6; -.
DR   STRING; 287.DR97_2432; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   PaxDb; Q9HUA6; -.
DR   PRIDE; Q9HUA6; -.
DR   DNASU; 879628; -.
DR   EnsemblBacteria; AAG08462; AAG08462; PA5077.
DR   GeneID; 879628; -.
DR   KEGG; pae:PA5077; -.
DR   PATRIC; fig|208964.12.peg.5322; -.
DR   PseudoCAP; PA5077; -.
DR   HOGENOM; CLU_015730_0_0_6; -.
DR   InParanoid; Q9HUA6; -.
DR   OMA; TAGLHYW; -.
DR   PhylomeDB; Q9HUA6; -.
DR   BioCyc; PAER208964:G1FZ6-5193-MON; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0016758; F:hexosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..861
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_0000210354"
FT   TRANSMEM        142..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        198..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        521..543
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        572..594
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        601..623
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        683..705
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
SQ   SEQUENCE   861 AA;  96995 MW;  63557B5A83107E7E CRC64;
     MNNPSTTKAP LADYLAHLPL AEEERERLGE SASFSELHAR LAGAEGAAAD AGGDPALASV
     RARLQLGTPE LDDAEMFGVD AQGRTFLKIS PPIRRTKVIP EPWRTNILVR GWRRLTGRSN
     PPKPKRALPR ARWQRVGSLR RFILLLLMLA QTSVATYYMK GILPYQGWAF VDLEELAQQS
     LLDTVQQVLP YVIQFGILAL FAILFCWVSA GFWTALMGFW ELLTGRDRYR ISGSSAGSEP
     IAADARTAIV MPICNEDVPR VFAGLRATVE SMAATGEMER FDFFVLSDTN DPDIAVAEQQ
     AWLELCRETK GFGKIFYRRR RRRVKRKSGN IDDFCRRWGG DYRYMVVMDA DSVMSGDCLA
     KLVRLMEANP EAGIIQTAPK ASGMDTLYAR MQQFATRVYG PLFTAGLHFW QLGESHYWGH
     NAIIRMQPFI DHCALAPLPG KGSFAGAILS HDFVEAALMR RAGWGVWIAY DLDGSYEELP
     PNLLDELKRD RRWCHGNLMN FRLFLVKGMH PVHRAVFLTG VMSYLSAPLW FFFLVLSTAL
     LAVHQLMEPQ YFLEPRQLFP IWPQWHPEKA IALFSTTLTL LFLPKLLSVM LIWAKGAKGF
     GGVIRVTLSM LLEMFFSVLL APVRMLFHTR FVLAAFLGWS VQWNSPQRDD DATPWSEAIR
     RHGMQTLLGI AWTLLVAWLN PRFLWWLSPI VGSLILSIPV SVISSRVKLG LRARDEKLFL
     IPEEYDTPRE LRATDEYTYE NRWHALKDGF LKAAVDPLLN ALACAMGTAR HNRAQAIETV
     RGERIGKAID KGPEQLDGAT RLALLSDPVA LSRLHTRVWE EDRDDWLGRW RKAEADDPHA
     ASVPLAQVVP GDAGLLPAAQ S