ID   OPGH_RALSO              Reviewed;         862 AA.
AC   Q8XVC2;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; Synonyms=mdoH;
GN   OrderedLocusNames=RSc2909; ORFNames=RS00341;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; AL646052; CAD16616.1; -; Genomic_DNA.
DR   RefSeq; WP_011002815.1; NC_003295.1.
DR   AlphaFoldDB; Q8XVC2; -.
DR   STRING; 267608.RSc2909; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   PRIDE; Q8XVC2; -.
DR   EnsemblBacteria; CAD16616; CAD16616; RSc2909.
DR   GeneID; 60502414; -.
DR   KEGG; rso:RSc2909; -.
DR   PATRIC; fig|267608.8.peg.2962; -.
DR   eggNOG; COG2943; Bacteria.
DR   eggNOG; COG3416; Bacteria.
DR   HOGENOM; CLU_015730_0_0_4; -.
DR   OMA; TAGLHYW; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000001436; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..862
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_0000210358"
FT   TRANSMEM        188..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        545..567
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        597..619
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        626..648
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        708..730
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   862 AA;  95447 MW;  1E36C2689E741EAF CRC64;
     MELPATSGLN AQPGNAEGTT ASTRPATALS VAERYLEALP LPAEARAALR REAGIEPADK
     DAVALAKLHR ALARLDAAQT ASIEGSVPAY ASIGSRLDAA YGTPHAGTAT PEPAPPLEHD
     TAGRIHLDTG PEPARRSMVP WPWVLGPIWR ARRAIGRLFS GGTAPVPYEQ PDSPDPKGIW
     RFVGARRRLT LLALMIAQTV AATWAMSSVL PYHGHDWLEA IIIALFALLF CWVSAGFWTA
     ITGFLLLAFH GDRFVISRRA APNAPIPDDA RTAIVMPICN EDVQRVFAGL RATYESLQRT
     GHLEHFDFFV LSDSGDPDIR TAEADAWLHV CRALDGFGRV FYRWRRHRVK RKSGNIDDFC
     RRWGGRYRYM IVLDADSVMS GDCLTRLVQL MEGAPSAGII QTAPLAAGRD TLYARIQQFA
     TRVYGPLFTA GLHYWQLGES HYWGHNAIIR LEPFIKHCAL APIPGKGSLS GEIMSHDFVE
     AALMRRAGWA VWIAYDLDGS YEEMPPNLLD ELGRDRRWCH GNLMNFRLFG SPGFHPVHRA
     VFVTGVMAYL SAPLWFLFLL LSTALLAKHT LIAPEYFTQP RQLFPIWPEW HPEKAAALFS
     ATATVLFLPK ILSVLVLWAK GPRRFGGAVH LALSMVIEAV FSVLAAPVRM LFHTRFVTAA
     FLGWKVHWKS PPRDDAQTHW GDAVRRHGLH TLLGLGWAAL VYWLNPSFLW WLSPVVGALI
     VSILLSVFSS RVTLGRGMRR WRLFMIPEEV RPPRELRAMR KHLRQAPPTP DFRLAVVDPV
     TNALMCAIGT ARFPHDPKLL EVRDATVLQA LAAGPDKLTS KQKLVLLSDP LALSALHLAV
     WSSDVHRAAW LPANALASKA AA