ID   OPGH_SHESM              Reviewed;         727 AA.
AC   Q0HJ63;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072};
GN   OrderedLocusNames=Shewmr4_1830;
OS   Shewanella sp. (strain MR-4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=60480;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MR-4;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K.,
RA   Konstantinidis K., Klappenbach J., Tiedje J., Richardson P.;
RT   "Complete sequence of Shewanella sp. MR-4.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; CP000446; ABI38904.1; -; Genomic_DNA.
DR   RefSeq; WP_011622601.1; NC_008321.1.
DR   AlphaFoldDB; Q0HJ63; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   KEGG; she:Shewmr4_1830; -.
DR   HOGENOM; CLU_015730_1_0_6; -.
DR   OMA; TAGLHYW; -.
DR   UniPathway; UPA00637; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF13632; Glyco_trans_2_3; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..727
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_1000064617"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        408..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        460..480
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        496..516
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        572..592
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   REGION          18..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   727 AA;  81033 MW;  72214A45D5DA019E CRC64;
     MTVSENSVLE TEVLVGGSAM PNERPGAMEP QSLSQMPEGF PRRSTVANGV RSKVSRRFFV
     VGGALLLSAF AIYEMGAVFS IGGITPLEYL MLVLFAINFC WIALAFCSGI AGFFMLLKKP
     KPNELEQTEL HTRTAILMPT YNESPDRVFS AVSVMAEALS QTGHGHAFDW FILSDTTDPE
     IALLEEQAFL VLRQETHKHS RVYYRRRRKN VARKAGNVAD FCRRWGSRYD HLLVLDADSL
     MESSTITGLA QRMQADPDAG LIQTIPSLIN GTTLMARLQQ FAARIYGPVI GTGLGWWVQK
     EGNFWGHNAI IRTEAFMGAA GLPNLKGKPP FGGHILSHDF VEAALIRRAG WSVVIAYDLP
     GSYEECPPSI VDLAVRDRRW CQGNLQHSRI LPTKGLHWVS RLHLMTGIMA YLSSPFWLLL
     ILTGLMLALQ AHFIRPEYFT DQFSLFPTWP IMDSDRALRL FYITMGVLFG PKIFGVLLLL
     KDGNFARSVG GRIKAILSVI FEVILSALIA PIMMFIHCGA VMSILMGRDS GWSPQRRDDG
     SMPWLTLIYR HRWHMLAGVM LGYAAILDSL TLLAWMSPAL IGLWLAVPIS AWTGSIKIGE
     FFKRIGILAT PEERNPAPIC IRAQEARAAY QAHIEQPWTL AQVLKDPALM ELHLAMVDKQ
     PLRAAGTPIE PVEAIVHVKV HEAQCQQSAL ALFNRQEMAL VLANPLMLRS LQKLPEQFVP
     EDLVSFC