ID   OPGH_XANC8              Reviewed;         645 AA.
AC   Q4UYZ8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE            EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN   Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; OrderedLocusNames=XC_0645;
OS   Xanthomonas campestris pv. campestris (strain 8004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xanthomonas.
OX   NCBI_TaxID=314565;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8004;
RX   PubMed=15899963; DOI=10.1101/gr.3378705;
RA   Qian W., Jia Y., Ren S.-X., He Y.-Q., Feng J.-X., Lu L.-F., Sun Q.,
RA   Ying G., Tang D.-J., Tang H., Wu W., Hao P., Wang L., Jiang B.-L., Zeng S.,
RA   Gu W.-Y., Lu G., Rong L., Tian Y., Yao Z., Fu G., Chen B., Fang R.,
RA   Qiang B., Chen Z., Zhao G.-P., Tang J.-L., He C.;
RT   "Comparative and functional genomic analyses of the pathogenicity of
RT   phytopathogen Xanthomonas campestris pv. campestris.";
RL   Genome Res. 15:757-767(2005).
CC   -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC       glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01072}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR   EMBL; CP000050; AAY47725.1; -; Genomic_DNA.
DR   RefSeq; WP_011038607.1; NC_007086.1.
DR   AlphaFoldDB; Q4UYZ8; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   EnsemblBacteria; AAY47725; AAY47725; XC_0645.
DR   KEGG; xcb:XC_0645; -.
DR   HOGENOM; CLU_015730_1_0_6; -.
DR   OMA; TAGLHYW; -.
DR   OrthoDB; 1049243at2; -.
DR   UniPathway; UPA00637; -.
DR   Proteomes; UP000000420; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016758; F:hexosyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.550.10; -; 1.
DR   HAMAP; MF_01072; MdoH_OpgH; 1.
DR   InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF13632; Glyco_trans_2_3; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW   Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..645
FT                   /note="Glucans biosynthesis glucosyltransferase H"
FT                   /id="PRO_1000064620"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        423..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        465..485
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        504..524
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        558..578
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   TRANSMEM        580..600
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   645 AA;  70020 MW;  D7C0723D696831AC CRC64;
     MDGTVTLSPA PTDLPPVSSL DAGQPTLPPE APLAMPEQSL REGSLQVRHQ RTSPMGIGLR
     RFYLIGGTLT ATAVAVWVML SVLWPGGFSV LEGCLLGLFV LLFAWIAMSF ASAVAGFITV
     VARAGRKLGI DPDAPLPSLH TRTALLMPTY NEDPRRLLAG LQAIYESVAE TGQLEHFDFF
     VLSDTTREHI GRAEEQVYAE LCDSVGGHGR IFYRRRADNA ARKAGNVADW VRRFGGNYPQ
     MLILDADSVM TGDTIVRLVA GMEDNPDVGL IQTLPAVVNG QTLFARMQQF GGRVYGPIIA
     FGVAWWHGAE SNYWGHNAII RTQAFADHAG LPSLRGRKPF GGHVLSHDFV EAALMRRGGW
     AMHMVPYLQG SYEEGPPTLT DLLVRDRRWC QGNLQHAKVV GAKGLHWISR MHMMIGIGHY
     FTAPMWGMLM LVGIGIPLAG AGIDLAQGLP FSPARYWHGS SDGNAIWIFV CTMFVLLAPK
     LLGYIALLLN PRERRACGGA IRAALSILLE TVLAALMAPV VMYLQSRGVF EVLAGKDSGW
     DAQVRDDGKL SWPALIRSYG GLSVFGLFMG TLAYLVSPSL AAWMAPVIVG MVVSIPVVAV
     TSLRRTGLAL RRAGIFCIPE ELDPPKVLVR ASELRRAAAL EPSLI