OPGH_XANCP
ID OPGH_XANCP Reviewed; 645 AA.
AC Q8P532;
DT 25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Glucans biosynthesis glucosyltransferase H {ECO:0000255|HAMAP-Rule:MF_01072};
DE EC=2.4.1.- {ECO:0000255|HAMAP-Rule:MF_01072};
GN Name=opgH {ECO:0000255|HAMAP-Rule:MF_01072}; Synonyms=hrpM;
GN OrderedLocusNames=XCC3515;
OS Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB
OS 528 / LMG 568 / P 25).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xanthomonas.
OX NCBI_TaxID=190485;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25;
RX PubMed=12024217; DOI=10.1038/417459a;
RA da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R.,
RA Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr.,
RA Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G.,
RA Cannavan F., Cardozo J., Chambergo F., Ciapina L.P., Cicarelli R.M.B.,
RA Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B.,
RA Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F.,
RA Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T.,
RA Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A.,
RA Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J.,
RA Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M.,
RA Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A.,
RA Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A.,
RA Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M.,
RA Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P.;
RT "Comparison of the genomes of two Xanthomonas pathogens with differing host
RT specificities.";
RL Nature 417:459-463(2002).
CC -!- FUNCTION: Involved in the biosynthesis of osmoregulated periplasmic
CC glucans (OPGs). {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- PATHWAY: Glycan metabolism; osmoregulated periplasmic glucan (OPG)
CC biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01072}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01072}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01072}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. OpgH
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_01072}.
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DR EMBL; AE008922; AAM42785.1; -; Genomic_DNA.
DR RefSeq; NP_638861.1; NC_003902.1.
DR RefSeq; WP_011038607.1; NC_003902.1.
DR AlphaFoldDB; Q8P532; -.
DR STRING; 340.xcc-b100_0681; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR EnsemblBacteria; AAM42785; AAM42785; XCC3515.
DR KEGG; xcc:XCC3515; -.
DR PATRIC; fig|190485.4.peg.3758; -.
DR eggNOG; COG2943; Bacteria.
DR HOGENOM; CLU_015730_1_0_6; -.
DR OMA; TAGLHYW; -.
DR UniPathway; UPA00637; -.
DR Proteomes; UP000001010; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016758; F:hexosyltransferase activity; IBA:GO_Central.
DR GO; GO:0009250; P:glucan biosynthetic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.550.10; -; 1.
DR HAMAP; MF_01072; MdoH_OpgH; 1.
DR InterPro; IPR023725; Glucans_biosynth_gluTrFase_H.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..645
FT /note="Glucans biosynthesis glucosyltransferase H"
FT /id="PRO_0000210368"
FT TRANSMEM 62..84
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 99..121
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 417..439
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 466..488
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 501..523
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 554..576
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT TRANSMEM 581..603
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01072"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 70020 MW; D7C0723D696831AC CRC64;
MDGTVTLSPA PTDLPPVSSL DAGQPTLPPE APLAMPEQSL REGSLQVRHQ RTSPMGIGLR
RFYLIGGTLT ATAVAVWVML SVLWPGGFSV LEGCLLGLFV LLFAWIAMSF ASAVAGFITV
VARAGRKLGI DPDAPLPSLH TRTALLMPTY NEDPRRLLAG LQAIYESVAE TGQLEHFDFF
VLSDTTREHI GRAEEQVYAE LCDSVGGHGR IFYRRRADNA ARKAGNVADW VRRFGGNYPQ
MLILDADSVM TGDTIVRLVA GMEDNPDVGL IQTLPAVVNG QTLFARMQQF GGRVYGPIIA
FGVAWWHGAE SNYWGHNAII RTQAFADHAG LPSLRGRKPF GGHVLSHDFV EAALMRRGGW
AMHMVPYLQG SYEEGPPTLT DLLVRDRRWC QGNLQHAKVV GAKGLHWISR MHMMIGIGHY
FTAPMWGMLM LVGIGIPLAG AGIDLAQGLP FSPARYWHGS SDGNAIWIFV CTMFVLLAPK
LLGYIALLLN PRERRACGGA IRAALSILLE TVLAALMAPV VMYLQSRGVF EVLAGKDSGW
DAQVRDDGKL SWPALIRSYG GLSVFGLFMG TLAYLVSPSL AAWMAPVIVG MVVSIPVVAV
TSLRRTGLAL RRAGIFCIPE ELDPPKVLVR ASELRRAAAL EPSLI
