OPI10_DROME
ID OPI10_DROME Reviewed; 197 AA.
AC Q9W0C7;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein OPI10 homolog;
GN ORFNames=CG13926;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
CC -!- SIMILARITY: Belongs to the OPI10 family. {ECO:0000305}.
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DR EMBL; AE014296; AAF47523.1; -; Genomic_DNA.
DR RefSeq; NP_647633.1; NM_139376.4.
DR AlphaFoldDB; Q9W0C7; -.
DR SMR; Q9W0C7; -.
DR BioGRID; 63726; 1.
DR STRING; 7227.FBpp0072703; -.
DR PaxDb; Q9W0C7; -.
DR PRIDE; Q9W0C7; -.
DR EnsemblMetazoa; FBtr0072823; FBpp0072703; FBgn0035243.
DR GeneID; 38192; -.
DR KEGG; dme:Dmel_CG13926; -.
DR UCSC; CG13926-RA; d. melanogaster.
DR FlyBase; FBgn0035243; CG13926.
DR VEuPathDB; VectorBase:FBgn0035243; -.
DR eggNOG; KOG4067; Eukaryota.
DR GeneTree; ENSGT00390000004056; -.
DR HOGENOM; CLU_084839_0_0_1; -.
DR InParanoid; Q9W0C7; -.
DR OMA; RMEQNPN; -.
DR OrthoDB; 1223488at2759; -.
DR PhylomeDB; Q9W0C7; -.
DR Reactome; R-DME-3371453; Regulation of HSF1-mediated heat shock response.
DR BioGRID-ORCS; 38192; 1 hit in 1 CRISPR screen.
DR GenomeRNAi; 38192; -.
DR PRO; PR:Q9W0C7; -.
DR Proteomes; UP000000803; Chromosome 3L.
DR Bgee; FBgn0035243; Expressed in spermathecum and 23 other tissues.
DR ExpressionAtlas; Q9W0C7; baseline and differential.
DR Genevisible; Q9W0C7; DM.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0030544; F:Hsp70 protein binding; IBA:GO_Central.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR InterPro; IPR008493; DUF775.
DR InterPro; IPR031318; OPI10.
DR PANTHER; PTHR12925; PTHR12925; 1.
DR Pfam; PF05603; DUF775; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..197
FT /note="Protein OPI10 homolog"
FT /id="PRO_0000328391"
SQ SEQUENCE 197 AA; 21860 MW; 11F79BE654AF3C72 CRC64;
MSLFGLIVSG RLPQSDFVAV DATKLLVNVP DIESVNYLVV FLTGVSPLPV GTSAAIYFSW
PDANAAPTWQ YLGHINNTKP SAIFKIAQLK KSHELEAQAH GMVFGSQEIS HIAQIGVSLE
PELTVAQQTP AVSTANDNKQ FGQRMLENFF NYASSFGVAA RDIPPISSET FVPFSVVQNW
YTNFQRRMEQ NPNFWKY
