ID   OPP22_HAEIF             Reviewed;         361 AA.
AC   P20149;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Outer membrane protein P2;
DE            Short=OMP P2;
DE   Flags: Precursor;
GN   Name=ompP2;
OS   Haemophilus influenzae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype B;
RX   PubMed=2535836; DOI=10.1128/iai.57.1.88-94.1989;
RA   Munson R.S. Jr., Tolan R.W. Jr.;
RT   "Molecular cloning, expression, and primary sequence of outer membrane
RT   protein P2 of Haemophilus influenzae type b.";
RL   Infect. Immun. 57:88-94(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype B;
RX   PubMed=2576096; DOI=10.1111/j.1365-2958.1989.tb00165.x;
RA   Munson R.S. Jr., Bailey C., Grass S.;
RT   "Diversity of the outer membrane protein P2 gene from major clones of
RT   Haemophilus influenzae type b.";
RL   Mol. Microbiol. 3:1797-1803(1989).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype B;
RX   PubMed=2538396; DOI=10.1128/iai.57.4.1100-1107.1989;
RA   Hansen E.J., Hasemann C., Clausell A., Capra J.D., Orth K., Moomaw C.R.,
RA   Slaughter C.A., Latimer J.L., Miller E.E.;
RT   "Primary structure of the porin protein of Haemophilus influenzae type b
RT   determined by nucleotide sequence analysis.";
RL   Infect. Immun. 57:1100-1107(1989).
CC   -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC       across the outer membrane. {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; J03359; AAA24993.1; -; Genomic_DNA.
DR   EMBL; A09003; CAA00819.1; -; Unassigned_DNA.
DR   PIR; A30542; A30542.
DR   RefSeq; WP_015701411.1; NZ_VOFX01000004.1.
DR   AlphaFoldDB; P20149; -.
DR   SMR; P20149; -.
DR   PRIDE; P20149; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   Pfam; PF13609; Porin_4; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..20
FT   CHAIN           21..361
FT                   /note="Outer membrane protein P2"
FT                   /id="PRO_0000025259"
SQ   SEQUENCE   361 AA;  39701 MW;  AF104C9CD8942D69 CRC64;
     MKKTLAALIV GAFAASAANA AVVYNNEGTN VELGGRLSII AEQSNSTVDN QKQQHGALRN
     QGSRFHIKAT HNFGDGFYAQ GYLETRFVTK ASENGSDNFG DITSKYAYVT LGNKAFGEVK
     LGRAKTIADG ITSAEDKEYG VLNNSDYIPT SGNTVGYTFK GIDGLVLGAN YLLAQKREGA
     KGENKRPNDK AGEVRIGEIN NGIQVGAKYD ANDIVAKIAY GRTNYKYNES DEHKQQLNGV
     LATLGYRFSD LGLLVSLDSG YAKTKNYKIK HEKRYFVSPG FQYELMEDTN VYGNFKYERT
     SVDQGEKTRE QAVLFGVDHK LHKQLLTYIE GAYARTRTTE TGKGVKTEKE KSVGVGLRVY
     F