ID   OPP2A_HAEIF             Reviewed;         367 AA.
AC   Q48219;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Outer membrane protein P2;
DE            Short=OMP P2;
DE   Flags: Precursor;
GN   Name=ompP2;
OS   Haemophilus influenzae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=3224A;
RX   PubMed=8412618; DOI=10.1006/mpat.1993.1044;
RA   Duim B., Dankert J., Jansen H.M., van Alphen L.;
RT   "Genetic analysis of the diversity in outer membrane protein P2 of non-
RT   encapsulated Haemophilus influenzae.";
RL   Microb. Pathog. 14:451-462(1993).
CC   -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC       across the outer membrane. {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X73390; CAA51807.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q48219; -.
DR   SMR; Q48219; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   Pfam; PF13609; Porin_4; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..20
FT   CHAIN           21..367
FT                   /note="Outer membrane protein P2"
FT                   /id="PRO_0000025267"
SQ   SEQUENCE   367 AA;  40019 MW;  64B02C96A4BB0E40 CRC64;
     MKKTLAALIV GAFAASAANA AVVYNNEGTN VELGGRLSII AEQSNSTIKD QKQQHGALRN
     QSSRFHIKAT HNFGDGFYAQ GYLETRLVSA QSGTESDNFG HIITKYAYVT LGNKAFGEVK
     LGRAKTIADG ITSAEDKEYG VLNNSKYIPT NGNTVGYTFK GIDGLVLGAN YLLAQERYKY
     GGAAGGAGGA GAVAGEVYPQ KISNGVQVGA KYDANNIIAG IAYGRTNYRE SIHEKDLGKK
     QQVNGALSTL GYRFSDLGLL VSLDSGYAKT KNYKDKHEKS YFVSPGFQYE LMEDTNFYGN
     FKYERNSVDQ GKKEREQAVL FGIDHKLHKQ VLTYIEGAYA RTRTNDKSKA EKTEKEKSVG
     VGLRVYF