ID   OPPA_HAEIN              Reviewed;         541 AA.
AC   P71370;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Periplasmic oligopeptide-binding protein;
DE   Flags: Precursor;
GN   Name=oppA; OrderedLocusNames=HI_1124;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: This protein is a component of the oligopeptide permease, a
CC       binding protein-dependent transport system, it binds peptides up to
CC       five amino acids long with high affinity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC22778.1; -; Genomic_DNA.
DR   RefSeq; NP_439281.1; NC_000907.1.
DR   RefSeq; WP_010869134.1; NC_000907.1.
DR   STRING; 71421.HI_1124; -.
DR   PRIDE; P71370; -.
DR   EnsemblBacteria; AAC22778; AAC22778; HI_1124.
DR   KEGG; hin:HI_1124; -.
DR   PATRIC; fig|71421.8.peg.1173; -.
DR   eggNOG; COG4166; Bacteria.
DR   HOGENOM; CLU_017028_0_3_6; -.
DR   OMA; YDFFTWE; -.
DR   PhylomeDB; P71370; -.
DR   BioCyc; HINF71421:G1GJ1-1159-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR   GO; GO:1904680; F:peptide transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015833; P:peptide transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR030678; Peptide/Ni-bd.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR023765; SBP_5_CS.
DR   InterPro; IPR000914; SBP_5_dom.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   PIRSF; PIRSF002741; MppA; 1.
DR   PROSITE; PS01040; SBP_BACTERIAL_5; 1.
PE   3: Inferred from homology;
KW   Peptide transport; Periplasm; Protein transport; Reference proteome;
KW   Signal; Transport.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..541
FT                   /note="Periplasmic oligopeptide-binding protein"
FT                   /id="PRO_0000031799"
SQ   SEQUENCE   541 AA;  60911 MW;  1B949C9617514A99 CRC64;
     MQHKLLFSAI ALALSYSAQA VIVPEGTQLD EKQHIVINNG AEPQSFDPHK TEGVPESNVA
     YQLLEGLVTS DSEGKLQPGA AESWENTPDF KTWTFHLRKD AKWSNGDPVT AHDFVFAWRR
     LVDPATAAPY ASYLSYLQVE NAQDIIDGKK KPAELGVEXK DDYTFVVHTT NPVPYTVSXX
     THQSLLPLPX KVVEKLGDAW VKKENYVGNG AYKLANHIIN EKIEFERNPL YWNDKETVIN
     SATFLAIENP STDVARYRAG DLDMTSYGLP PEQFAKLQKE LPGEVYVTRT LGTYSYELNN
     KKAPFDNVNI RKALNLSLDR NVITDKVLGQ GQTPTYVFTP TYIEEGHLIQ QPAYSKEPMA
     QRNEEAIKLL EEAGYSKANP LKFSILYNTN ENHKKVAIAA ASMWKANTKG LIDVKLENQE
     WKTYIDSRRA GRYDVARAGW NADYNQATTF GNYFLSNSSN NTAKYANPEY DKAMAESYAA
     TDAEGRAKAY AKAEEILGKD YGIVPIFNYV NPRLVKPYVK GYSGKDPQDH IYLRNLYIIK
     H