ID   OPPA_LACLL              Reviewed;         600 AA.
AC   Q07741;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Oligopeptide-binding protein OppA;
DE   Flags: Precursor;
GN   Name=oppA;
OS   Lactococcus lactis subsp. lactis (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=1360;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SSL135;
RX   PubMed=8244921; DOI=10.1128/jb.175.23.7523-7532.1993;
RA   Tynkkynen S., Buist G., Kunji E., Kok J., Poolman B., Venema G.,
RA   Haandrikman A.;
RT   "Genetic and biochemical characterization of the oligopeptide transport
RT   system of Lactococcus lactis.";
RL   J. Bacteriol. 175:7523-7532(1993).
CC   -!- FUNCTION: This protein is a component of the oligopeptide permease, a
CC       binding protein-dependent transport system, it binds peptides up to
CC       five amino acids long with high affinity.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC       {ECO:0000305}.
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DR   EMBL; L18760; AAA16167.1; -; Unassigned_DNA.
DR   PIR; E53290; E53290.
DR   RefSeq; WP_011834693.1; NZ_WJUQ01000082.1.
DR   RefSeq; YP_004761502.1; NC_015862.1.
DR   AlphaFoldDB; Q07741; -.
DR   SMR; Q07741; -.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProt.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR030678; Peptide/Ni-bd.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR023765; SBP_5_CS.
DR   InterPro; IPR000914; SBP_5_dom.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   PIRSF; PIRSF002741; MppA; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS01040; SBP_BACTERIAL_5; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Peptide transport;
KW   Protein transport; Signal; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000305"
FT   CHAIN           23..600
FT                   /note="Oligopeptide-binding protein OppA"
FT                   /id="PRO_0000031795"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   600 AA;  65841 MW;  8CA880BEF1B5D3F1 CRC64;
     MNKLKVTLLA SSVVLAATLL SACGSNQSSS TSTKKLKAGN FDVAYQNPDK AIKGGNLKVA
     YQSDSPMKAQ WLSGLSNDAT FATMSGPGGG QDGLFFTDSG FKFIKGGAAD VALDKESKTA
     TITLRKDLKW SDGSEVTAKD YEFTYETIAN PAYGSDRWTD SLANIVGLSD YHTGKAKTIS
     GITFPDGENG KVIKVQFKEM KPGMTQSGNG YFLETVAPYQ YLKDVAPKDL ASSPKTTTKP
     LVTGPFKPEN VVAGESIKYV PNPYYWGEKP KLNSITYEVV STAKSVAALS SSKYDIINGM
     VSSQYKQVKN LKGYKVLGQQ AMYISLMYYN LGHYDAKNSI NVQDRKTPLQ DQNVRQAIGY
     ARNVAEVDNK FSNGLSTPAN SLIPPIFKQF TSSSVKGYEK QDLDKANKLL DEDGWKLNKS
     TGYREKDGKE LSLVYAARVG DANAETIAQN YIQQWKKIGV KVSLYNGKLM EFNSWVDHMT
     TPPGANDWDI TDGSWSLASE PSQQDLFSAA APYNFGHFND SEITKDLNDI DSAKSENPTY
     RKAAFVKYQE DMNKKAYVIP TNFMLNYTPV NKRVVGMTLD YGAMNTWSEI GVSSAKLATK