OPPB_ECO57
ID OPPB_ECO57 Reviewed; 306 AA.
AC P0AFH4; P31132; P76026; P77550;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Oligopeptide transport system permease protein OppB;
GN Name=oppB; OrderedLocusNames=Z2020, ECs1744;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides; probably responsible for the translocation of the
CC substrate across the membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; AE005174; AAG56099.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB35167.1; -; Genomic_DNA.
DR PIR; H90846; H90846.
DR RefSeq; NP_309771.1; NC_002695.1.
DR RefSeq; WP_000911112.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P0AFH4; -.
DR SMR; P0AFH4; -.
DR STRING; 155864.EDL933_1948; -.
DR EnsemblBacteria; AAG56099; AAG56099; Z2020.
DR EnsemblBacteria; BAB35167; BAB35167; ECs_1744.
DR GeneID; 66674935; -.
DR GeneID; 913107; -.
DR KEGG; ece:Z2020; -.
DR KEGG; ecs:ECs_1744; -.
DR PATRIC; fig|386585.9.peg.1846; -.
DR eggNOG; COG0601; Bacteria.
DR HOGENOM; CLU_036879_0_0_6; -.
DR OMA; FLMVNVM; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR045621; BPD_transp_1_N.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF19300; BPD_transp_1_N; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..306
FT /note="Oligopeptide transport system permease protein OppB"
FT /id="PRO_0000060144"
FT TOPO_DOM 1..9
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 31..99
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 100..121
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 122..137
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 159..172
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 173..190
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 191..226
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 227..250
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 251..271
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 272..293
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 294..306
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT DOMAIN 94..293
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 306 AA; 33443 MW; F74579B3F9EA4615 CRC64;
MLKFILRRCL EAIPTLFILI TISFFMMRLA PGSPFTGERT LPPEVMANIE AKYHLNDPIM
TQYFSYLKQL AHGDFGPSFK YKDYSVNDLV ASSFPVSAKL GAAAFFLAVI LGVSAGVIAA
LKQNTKWDYT VMGLAMTGVV IPSFVVAPLL VMIFAIILHW LPGGGWNGGA LKFMILPMVA
LSLAYIASIA RITRGSMIEV LHSNFIRTAR AKGLPMRRII LRHALKPALL PVLSYMGPAF
VGIITGSMVI ETIYGLPGIG QLFVNGALNR DYSLVLSLTI LVGALTILFN AIVDVLYAVI
DPKIRY
