OPPB_ECOLI
ID OPPB_ECOLI Reviewed; 306 AA.
AC P0AFH2; P31132; P76026; P77550;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Oligopeptide transport system permease protein OppB;
GN Name=oppB; OrderedLocusNames=b1244, JW1236;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-16.
RX PubMed=2187863; DOI=10.1016/s0021-9258(19)38898-2;
RA Kashiwagi K., Yamaguchi Y., Sakai Y., Kobayashi H., Igarashi K.;
RT "Identification of the polyamine-induced protein as a periplasmic
RT oligopeptide binding protein.";
RL J. Biol. Chem. 265:8387-8391(1990).
RN [5]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides; probably responsible for the translocation of the
CC substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; U00096; AAC74326.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA14776.1; -; Genomic_DNA.
DR EMBL; J05433; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; G64871; B36263.
DR RefSeq; NP_415760.1; NC_000913.3.
DR RefSeq; WP_000911112.1; NZ_STEB01000005.1.
DR AlphaFoldDB; P0AFH2; -.
DR SMR; P0AFH2; -.
DR BioGRID; 4261152; 281.
DR ComplexPortal; CPX-4343; Murein tripeptide ABC transporter complex.
DR ComplexPortal; CPX-4344; Oligopeptide ABC transporter complex.
DR DIP; DIP-48074N; -.
DR STRING; 511145.b1244; -.
DR TCDB; 3.A.1.5.41; the atp-binding cassette (abc) superfamily.
DR jPOST; P0AFH2; -.
DR PaxDb; P0AFH2; -.
DR PRIDE; P0AFH2; -.
DR EnsemblBacteria; AAC74326; AAC74326; b1244.
DR EnsemblBacteria; BAA14776; BAA14776; BAA14776.
DR GeneID; 66674935; -.
DR GeneID; 945823; -.
DR KEGG; ecj:JW1236; -.
DR KEGG; eco:b1244; -.
DR PATRIC; fig|1411691.4.peg.1039; -.
DR EchoBASE; EB0669; -.
DR eggNOG; COG0601; Bacteria.
DR InParanoid; P0AFH2; -.
DR OMA; FLMVNVM; -.
DR PhylomeDB; P0AFH2; -.
DR BioCyc; EcoCyc:OPPB-MON; -.
DR BioCyc; MetaCyc:OPPB-MON; -.
DR PRO; PR:P0AFH2; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0140205; P:oligopeptide import across plasma membrane; IC:ComplexPortal.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0140207; P:tripeptide import across plasma membrane; IC:ComplexPortal.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR045621; BPD_transp_1_N.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF19300; BPD_transp_1_N; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..306
FT /note="Oligopeptide transport system permease protein OppB"
FT /id="PRO_0000060143"
FT TOPO_DOM 1..9
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 31..99
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 100..121
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 122..137
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 159..172
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 173..190
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 191..226
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 227..250
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 251..271
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 272..293
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 294..306
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT DOMAIN 94..293
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 306 AA; 33443 MW; F74579B3F9EA4615 CRC64;
MLKFILRRCL EAIPTLFILI TISFFMMRLA PGSPFTGERT LPPEVMANIE AKYHLNDPIM
TQYFSYLKQL AHGDFGPSFK YKDYSVNDLV ASSFPVSAKL GAAAFFLAVI LGVSAGVIAA
LKQNTKWDYT VMGLAMTGVV IPSFVVAPLL VMIFAIILHW LPGGGWNGGA LKFMILPMVA
LSLAYIASIA RITRGSMIEV LHSNFIRTAR AKGLPMRRII LRHALKPALL PVLSYMGPAF
VGIITGSMVI ETIYGLPGIG QLFVNGALNR DYSLVLSLTI LVGALTILFN AIVDVLYAVI
DPKIRY
