OPPB_SALTY
ID OPPB_SALTY Reviewed; 306 AA.
AC P08005;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1988, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Oligopeptide transport system permease protein OppB;
GN Name=oppB; OrderedLocusNames=STM1745;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=2821267; DOI=10.1016/0022-2836(87)90332-9;
RA Hiles I.D., Gallagher M.P., Jamieson D.J., Higgins C.F.;
RT "Molecular characterization of the oligopeptide permease of Salmonella
RT typhimurium.";
RL J. Mol. Biol. 195:125-142(1987).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP TOPOLOGY.
RX PubMed=1738314; DOI=10.1111/j.1365-2958.1992.tb00836.x;
RA Pearce S.R., Mimmack M.L., Gallagher M.P., Gileadi U., Hyde S.C.,
RA Higgins C.F.;
RT "Membrane topology of the integral membrane components, OppB and OppC, of
RT the oligopeptide permease of Salmonella typhimurium.";
RL Mol. Microbiol. 6:47-57(1992).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides; probably responsible for the translocation of the
CC substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; X05491; CAA29040.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20663.1; -; Genomic_DNA.
DR PIR; B29333; QREBOB.
DR RefSeq; NP_460704.1; NC_003197.2.
DR RefSeq; WP_000911097.1; NC_003197.2.
DR AlphaFoldDB; P08005; -.
DR SMR; P08005; -.
DR STRING; 99287.STM1745; -.
DR TCDB; 3.A.1.5.1; the atp-binding cassette (abc) superfamily.
DR PaxDb; P08005; -.
DR EnsemblBacteria; AAL20663; AAL20663; STM1745.
DR GeneID; 1253264; -.
DR KEGG; stm:STM1745; -.
DR PATRIC; fig|99287.12.peg.1842; -.
DR HOGENOM; CLU_036879_0_0_6; -.
DR OMA; FLMVNVM; -.
DR PhylomeDB; P08005; -.
DR BioCyc; SENT99287:STM1745-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR045621; BPD_transp_1_N.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF19300; BPD_transp_1_N; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..306
FT /note="Oligopeptide transport system permease protein OppB"
FT /id="PRO_0000060146"
FT TOPO_DOM 1..9
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 31..99
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 100..121
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 122..137
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 159..172
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 173..190
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 191..226
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 227..250
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 251..271
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 272..293
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 294..306
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT DOMAIN 94..293
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 306 AA; 33420 MW; B1F1E3A1B1AE5244 CRC64;
MLKFILRRCL EAIPTLFILI TISFFMMRLA PGSPFTGERA LPPEVLANIE AKYHLNDPIM
TQYFSYLKQL AHGDFGPSFK YKDYTVNDLV AASFPVSAKL GAAAFLLAVI IGVSAGVIAA
LKQNTRWDYT VMGFAMTGVV IPSFVVAPLL VMVFAITLQW LPGGGWNGGA LKFMILPMVA
LSLAYIASIA RITRGSMIEV LHSNFIRTAR AKGLPMRRII FRHALKPALL PVLSYMGPAF
VGIITGSMVI ETIYGLPGIG QLFVNGALNR DYSLVLSLTI LVGALTILFN AIVDVLYAVI
DPKIRY
