OPPC_ECO57
ID OPPC_ECO57 Reviewed; 302 AA.
AC P0AFH7; P77664;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Oligopeptide transport system permease protein OppC;
GN Name=oppC; OrderedLocusNames=Z2021, ECs1745;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides; probably responsible for the translocation of the
CC substrate across the membrane. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; AE005174; AAG56100.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB35168.1; -; Genomic_DNA.
DR PIR; A99847; A99847.
DR PIR; H85704; H85704.
DR RefSeq; NP_309772.1; NC_002695.1.
DR RefSeq; WP_000979661.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P0AFH7; -.
DR STRING; 155864.EDL933_1949; -.
DR EnsemblBacteria; AAG56100; AAG56100; Z2021.
DR EnsemblBacteria; BAB35168; BAB35168; ECs_1745.
DR GeneID; 66674934; -.
DR GeneID; 913106; -.
DR KEGG; ece:Z2021; -.
DR KEGG; ecs:ECs_1745; -.
DR PATRIC; fig|386585.9.peg.1847; -.
DR eggNOG; COG1173; Bacteria.
DR HOGENOM; CLU_028518_1_3_6; -.
DR OMA; YYRVVRN; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR025966; OppC_N.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF12911; OppC_N; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..302
FT /note="Oligopeptide transport system permease protein OppC"
FT /id="PRO_0000060150"
FT TOPO_DOM 1..37
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 60..102
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 123..139
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 161..163
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 164..180
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 181..215
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 237..267
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 268..290
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 291..302
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT DOMAIN 101..290
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 302 AA; 33022 MW; 875829FDFFF513D3 CRC64;
MMLSKKNSET LENFSEKLEV EGRSLWQDAR RRFMHNRAAV ASLIVLVLIA LFVILAPMLS
QFAYDDTDWA MMSSAPDMES GHYFGTDSSG RDLLVRVAIG GRISLMVGVA AALVAVVVGT
LYGSLSGYLG GKVDSVMMRL LEILNSFPFM FFVILLVTFF GQNILLIFVA IGMVSWLDMA
RIVRGQTLSL KRKEFIEAAQ VGGVSTSGIV IRHIVPNVLG VVVVYASLLV PSMILFESFL
SFLGLGTQEP LSSWGALLSD GANSMEVSPW LLLFPAGFLV VTLFCFNFIG DGLRDALDPK
DR
