OPPC_ECOLI
ID OPPC_ECOLI Reviewed; 302 AA.
AC P0AFH6; P77664;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Oligopeptide transport system permease protein OppC;
GN Name=oppC; OrderedLocusNames=b1245, JW1237;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides; probably responsible for the translocation of the
CC substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; U00096; AAC74327.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA14777.1; -; Genomic_DNA.
DR PIR; H64871; H64871.
DR RefSeq; NP_415761.1; NC_000913.3.
DR RefSeq; WP_000979661.1; NZ_STEB01000005.1.
DR AlphaFoldDB; P0AFH6; -.
DR BioGRID; 4261369; 446.
DR ComplexPortal; CPX-4343; Murein tripeptide ABC transporter complex.
DR ComplexPortal; CPX-4344; Oligopeptide ABC transporter complex.
DR STRING; 511145.b1245; -.
DR TCDB; 3.A.1.5.41; the atp-binding cassette (abc) superfamily.
DR jPOST; P0AFH6; -.
DR PaxDb; P0AFH6; -.
DR PRIDE; P0AFH6; -.
DR EnsemblBacteria; AAC74327; AAC74327; b1245.
DR EnsemblBacteria; BAA14777; BAA14777; BAA14777.
DR GeneID; 66674934; -.
DR GeneID; 945810; -.
DR KEGG; ecj:JW1237; -.
DR KEGG; eco:b1245; -.
DR PATRIC; fig|1411691.4.peg.1038; -.
DR EchoBASE; EB0670; -.
DR eggNOG; COG1173; Bacteria.
DR HOGENOM; CLU_028518_1_3_6; -.
DR InParanoid; P0AFH6; -.
DR OMA; YYRVVRN; -.
DR PhylomeDB; P0AFH6; -.
DR BioCyc; EcoCyc:OPPC-MON; -.
DR BioCyc; MetaCyc:OPPC-MON; -.
DR PRO; PR:P0AFH6; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0140205; P:oligopeptide import across plasma membrane; IC:ComplexPortal.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0140207; P:tripeptide import across plasma membrane; IC:ComplexPortal.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR025966; OppC_N.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF12911; OppC_N; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..302
FT /note="Oligopeptide transport system permease protein OppC"
FT /id="PRO_0000060149"
FT TOPO_DOM 1..37
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 60..102
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 123..139
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 161..163
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 164..180
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 181..215
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 237..267
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 268..290
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 291..302
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT DOMAIN 101..290
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 302 AA; 33022 MW; 875829FDFFF513D3 CRC64;
MMLSKKNSET LENFSEKLEV EGRSLWQDAR RRFMHNRAAV ASLIVLVLIA LFVILAPMLS
QFAYDDTDWA MMSSAPDMES GHYFGTDSSG RDLLVRVAIG GRISLMVGVA AALVAVVVGT
LYGSLSGYLG GKVDSVMMRL LEILNSFPFM FFVILLVTFF GQNILLIFVA IGMVSWLDMA
RIVRGQTLSL KRKEFIEAAQ VGGVSTSGIV IRHIVPNVLG VVVVYASLLV PSMILFESFL
SFLGLGTQEP LSSWGALLSD GANSMEVSPW LLLFPAGFLV VTLFCFNFIG DGLRDALDPK
DR
