OPPC_LACLS
ID OPPC_LACLS Reviewed; 294 AA.
AC P0A4P0; Q02VA8; Q07743;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 2.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Oligopeptide transport system permease protein OppC;
GN Name=oppC; OrderedLocusNames=LACR_D18;
OS Lactococcus lactis subsp. cremoris (strain SK11).
OG Plasmid pSK11L, and Plasmid pLACR4.
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus; Lactococcus cremoris subsp. cremoris.
OX NCBI_TaxID=272622;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC PLASMID=pSK11L;
RX PubMed=8586224;
RA Yu W., Gillies K., Kondo J.K., Broadbent J.R., McKay L.L.;
RT "Plasmid-mediated oligopeptide transport system in lactococci.";
RL Dev. Biol. Stand. 85:509-521(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK11; PLASMID=pLACR4;
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T.,
RA Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides; probably responsible for the translocation of the
CC substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; U09553; AAB00536.1; -; Unassigned_DNA.
DR EMBL; M76471; AAA25166.1; -; Genomic_DNA.
DR EMBL; CP000429; ABJ74114.1; -; Genomic_DNA.
DR RefSeq; WP_011669111.1; NC_008506.1.
DR AlphaFoldDB; P0A4P0; -.
DR EnsemblBacteria; ABJ74114; ABJ74114; LACR_D18.
DR KEGG; llc:LACR_D18; -.
DR HOGENOM; CLU_028518_1_4_9; -.
DR OMA; PSPPTWM; -.
DR Proteomes; UP000000240; Plasmid pLACR4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Peptide transport; Plasmid; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..294
FT /note="Oligopeptide transport system permease protein OppC"
FT /id="PRO_0000060138"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 202..224
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 88..280
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT CONFLICT 67
FT /note="T -> N (in Ref. 1; AAA25166/AAB00536)"
FT /evidence="ECO:0000305"
FT CONFLICT 185
FT /note="Q -> R (in Ref. 1; AAA25166/AAB00536)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 294 AA; 32794 MW; 556F5F453752CF26 CRC64;
MTEKKHKNSL SLVHSIKEEL KKDKLAMIST IFLVAVFLIV YIYSMFLKQS NYVDVNIMDQ
YLAPLTTGHL LGTDNGGRDI IMMLMISARN SFNIAFAVTL ITLVVGNILG VITGYFGGRF
DLIFMRFTDF VMILPSMMII IVFVTIIPRF NSWSLIGIIS IFSWIGTTRL IRARTMTEVN
RDYVQASKTS GTSDFKIMFR EIWPNLSTLV IAEATLVFAG NIGLETGLSF LGFGLPAGTP
SLGTMINEAT NPETMTDKPW TWVPATVVIL IVVLAIIFIG NALRRVADQR QATR
