OPPC_SALTY
ID OPPC_SALTY Reviewed; 302 AA.
AC P08006;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1988, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Oligopeptide transport system permease protein OppC;
GN Name=oppC; OrderedLocusNames=STM1744;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=2821267; DOI=10.1016/0022-2836(87)90332-9;
RA Hiles I.D., Gallagher M.P., Jamieson D.J., Higgins C.F.;
RT "Molecular characterization of the oligopeptide permease of Salmonella
RT typhimurium.";
RL J. Mol. Biol. 195:125-142(1987).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP TOPOLOGY.
RX PubMed=1738314; DOI=10.1111/j.1365-2958.1992.tb00836.x;
RA Pearce S.R., Mimmack M.L., Gallagher M.P., Gileadi U., Hyde S.C.,
RA Higgins C.F.;
RT "Membrane topology of the integral membrane components, OppB and OppC, of
RT the oligopeptide permease of Salmonella typhimurium.";
RL Mol. Microbiol. 6:47-57(1992).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides; probably responsible for the translocation of the
CC substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. OppBC subfamily. {ECO:0000305}.
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DR EMBL; X05491; CAA29041.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20662.1; -; Genomic_DNA.
DR PIR; C29333; QREBOC.
DR RefSeq; NP_460703.1; NC_003197.2.
DR RefSeq; WP_000979653.1; NC_003197.2.
DR AlphaFoldDB; P08006; -.
DR STRING; 99287.STM1744; -.
DR TCDB; 3.A.1.5.1; the atp-binding cassette (abc) superfamily.
DR PaxDb; P08006; -.
DR EnsemblBacteria; AAL20662; AAL20662; STM1744.
DR GeneID; 1253263; -.
DR KEGG; stm:STM1744; -.
DR PATRIC; fig|99287.12.peg.1841; -.
DR HOGENOM; CLU_028518_1_3_6; -.
DR OMA; YYRVVRN; -.
DR PhylomeDB; P08006; -.
DR BioCyc; SENT99287:STM1744-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR InterPro; IPR025966; OppC_N.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF12911; OppC_N; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..302
FT /note="Oligopeptide transport system permease protein OppC"
FT /id="PRO_0000060151"
FT TOPO_DOM 1..37
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 60..102
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 123..139
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 161..163
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 164..180
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 181..215
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 237..267
FT /note="Extracellular"
FT /evidence="ECO:0000305|PubMed:1738314"
FT TRANSMEM 268..290
FT /note="Helical"
FT /evidence="ECO:0000305"
FT TOPO_DOM 291..302
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305|PubMed:1738314"
FT DOMAIN 101..290
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 302 AA; 33090 MW; 0E6FE57404F7339E CRC64;
MMLSKKNSET LENFSEKLEV EGRSLWQDAR RRFMHNRAAV ASLIVLFLIA LFVTVAPMLS
QFTYFDTDWG MMSSAPDMAS GHYFGTDSSG RDLLVRVAIG GRISLMVGIA AALVAVIVGT
LYGSLSGYLG GKIDSVMMRL LEILNSFPFM FFVILLVTFF GQNILLIFVA IGMVSWLDMA
RIVRGQTLSL KRKEFIEAAQ VGGVSTASIV IRHIVPNVLG VVVVYASLLV PSMILFESFL
SFLGLGTQEP LSSWGALLSD GANSMEVSPW LLLFPAGFLV VTLFCFNFIG DGLRDALDPK
DR
