OPPD_LACLA
ID OPPD_LACLA Reviewed; 338 AA.
AC Q07733;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 2.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Oligopeptide transport ATP-binding protein OppD;
GN Name=oppD; OrderedLocusNames=LL1841; ORFNames=L93148;
OS Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=272623;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SSL135;
RX PubMed=8244921; DOI=10.1128/jb.175.23.7523-7532.1993;
RA Tynkkynen S., Buist G., Kunji E., Kok J., Poolman B., Venema G.,
RA Haandrikman A.;
RT "Genetic and biochemical characterization of the oligopeptide transport
RT system of Lactococcus lactis.";
RL J. Bacteriol. 175:7523-7532(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL1403;
RX PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA Ehrlich S.D., Sorokin A.;
RT "The complete genome sequence of the lactic acid bacterium Lactococcus
RT lactis ssp. lactis IL1403.";
RL Genome Res. 11:731-753(2001).
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC oligopeptides. Probably responsible for energy coupling to the
CC transport system.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; L18760; AAA16163.1; -; Unassigned_DNA.
DR EMBL; AE005176; AAK05939.1; -; Genomic_DNA.
DR PIR; A53290; A53290.
DR PIR; A86855; A86855.
DR RefSeq; NP_267998.1; NC_002662.1.
DR RefSeq; WP_010906165.1; NC_002662.1.
DR AlphaFoldDB; Q07733; -.
DR SMR; Q07733; -.
DR STRING; 272623.L93148; -.
DR TCDB; 3.A.1.5.10; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q07733; -.
DR EnsemblBacteria; AAK05939; AAK05939; L93148.
DR KEGG; lla:L93148; -.
DR PATRIC; fig|272623.7.peg.1972; -.
DR eggNOG; COG0444; Bacteria.
DR HOGENOM; CLU_000604_1_23_9; -.
DR OMA; GSMPRID; -.
DR Proteomes; UP000002196; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013563; Oligopep_ABC_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF08352; oligo_HPY; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR01727; oligo_HPY; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW Peptide transport; Protein transport; Reference proteome; Transport.
FT CHAIN 1..338
FT /note="Oligopeptide transport ATP-binding protein OppD"
FT /id="PRO_0000092654"
FT DOMAIN 7..257
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 43..50
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT CONFLICT 34
FT /note="R -> K (in Ref. 1; AAA16163)"
FT /evidence="ECO:0000305"
FT CONFLICT 75
FT /note="E -> D (in Ref. 1; AAA16163)"
FT /evidence="ECO:0000305"
FT CONFLICT 239
FT /note="A -> T (in Ref. 1; AAA16163)"
FT /evidence="ECO:0000305"
FT CONFLICT 282
FT /note="E -> K (in Ref. 1; AAA16163)"
FT /evidence="ECO:0000305"
FT CONFLICT 337
FT /note="K -> E (in Ref. 1; AAA16163)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 338 AA; 37383 MW; 1E9BCB8142DB01D0 CRC64;
MESENILEAK QVSVAFRIAG KFQKAIYDID LSLRRGEVLA IVGESGSGKS TFATAVMGLH
NPNQTQITGS ILLDEEEVIG KTGDSMASIR GSKVGMIFQN PLTALNPLMK IGQQIKEMLA
VHDVYPENQY ESRIFQLLEQ VGIPNPKRVV NQFPHQLSGG MRQRVMIAIA IANDPDLIIA
DEPTTALDVT IQAQILDLIL EIQKKKNAGV ILITHDLGVV AEVADTVAVM YAGQLVEKAS
VEELFQNPKH PYTRSLLRSN PSAETVSDDL YVIPGSVPSL SEIEYDKDLF LARVPWMKEE
AQKVISEKMT EISSNHFVRG QAWKKFEFPD QKLKGGKK
