ID   OPPF_LACLS              Reviewed;         319 AA.
AC   P0A2V5; P50981; Q02VA6; Q07734;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Oligopeptide transport ATP-binding protein OppF;
GN   Name=oppF; OrderedLocusNames=LACR_D20;
OS   Lactococcus lactis subsp. cremoris (strain SK11).
OG   Plasmid pSK11L, and Plasmid pLACR4.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus; Lactococcus cremoris subsp. cremoris.
OX   NCBI_TaxID=272622;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=pSK11L;
RX   PubMed=8586224;
RA   Yu W., Gillies K., Kondo J.K., Broadbent J.R., McKay L.L.;
RT   "Plasmid-mediated oligopeptide transport system in lactococci.";
RL   Dev. Biol. Stand. 85:509-521(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK11; PLASMID=pLACR4;
RX   PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA   Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V.,
RA   Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA   Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA   Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA   Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA   Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA   Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R.,
RA   O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T.,
RA   Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
RT   "Comparative genomics of the lactic acid bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       oligopeptides. Probably responsible for energy coupling to the
CC       transport system.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U09553; AAB00534.1; -; Unassigned_DNA.
DR   EMBL; CP000429; ABJ74116.1; -; Genomic_DNA.
DR   RefSeq; WP_010906164.1; NC_008506.1.
DR   RefSeq; YP_005863099.1; NC_017478.1.
DR   AlphaFoldDB; P0A2V5; -.
DR   SMR; P0A2V5; -.
DR   EnsemblBacteria; ABJ74116; ABJ74116; LACR_D20.
DR   KEGG; llc:LACR_D20; -.
DR   HOGENOM; CLU_000604_1_23_9; -.
DR   OMA; GRYPHMF; -.
DR   Proteomes; UP000000240; Plasmid pLACR4.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013563; Oligopep_ABC_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08352; oligo_HPY; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Peptide transport; Plasmid; Protein transport; Transport.
FT   CHAIN           1..319
FT                   /note="Oligopeptide transport ATP-binding protein OppF"
FT                   /id="PRO_0000092663"
FT   DOMAIN          5..255
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         48..55
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   319 AA;  35976 MW;  5401311031DD13FF CRC64;
     MSEILNLKDL KVYYPIRSGF FNRVTDNVLA VDGVDLTIHE GETVGLVGES GSGKSTIGKT
     IVGLEQMTSG QLIYKGQDVS KKKIRNQLKY NKDVQMIFQD AFSSLNPRKT IYDIIAEPIR
     NFEKIDANTE NKRIHELLDI VGLPKQALEQ YPFQFSGGQQ QRIGIARAVA TNPKLIVADE
     PVSALDLSVQ AQVLNFMKLI QKDLGIAFLF ISHDLGVVRH MTDNIAVMHN GRIVEKGTRR
     DIFDEPQHIY TKRLLSAIPS IDVTRRAENR KNRLKVEQDF EDKKANFYDK DGHALPLKKL
     SESHWAALPK GGENVESNY