ID   OPPF_STRMU              Reviewed;         308 AA.
AC   P72479;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2002, sequence version 2.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Oligopeptide transport ATP-binding protein OppF;
GN   Name=oppF; OrderedLocusNames=SMU_259;
OS   Streptococcus mutans serotype c (strain ATCC 700610 / UA159).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=210007;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700610 / UA159;
RX   PubMed=12397186; DOI=10.1073/pnas.172501299;
RA   Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B.,
RA   Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S.,
RA   Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J.;
RT   "Genome sequence of Streptococcus mutans UA159, a cariogenic dental
RT   pathogen.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-97.
RC   STRAIN=GS-5;
RA   Peruzzi F., Piggot P.J., Daneo-Moore L.;
RL   Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       oligopeptides. Probably responsible for energy coupling to the
CC       transport system (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB41195.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE014133; AAN58028.1; -; Genomic_DNA.
DR   EMBL; U75477; AAB41195.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_720722.1; NC_004350.2.
DR   RefSeq; WP_002262736.1; NC_004350.2.
DR   AlphaFoldDB; P72479; -.
DR   SMR; P72479; -.
DR   STRING; 210007.SMU_259; -.
DR   PRIDE; P72479; -.
DR   EnsemblBacteria; AAN58028; AAN58028; SMU_259.
DR   KEGG; smu:SMU_259; -.
DR   PATRIC; fig|210007.7.peg.225; -.
DR   eggNOG; COG4608; Bacteria.
DR   HOGENOM; CLU_000604_1_23_9; -.
DR   OMA; VFYKGQD; -.
DR   PhylomeDB; P72479; -.
DR   Proteomes; UP000002512; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013563; Oligopep_ABC_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08352; oligo_HPY; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Peptide transport; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..308
FT                   /note="Oligopeptide transport ATP-binding protein OppF"
FT                   /id="PRO_0000092664"
FT   DOMAIN          9..254
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         46..53
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   CONFLICT        9
FT                   /note="V -> I (in Ref. 2; AAB41195)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        35
FT                   /note="N -> D (in Ref. 2; AAB41195)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   308 AA;  34842 MW;  E9C9D4E74435541D CRC64;
     MTENRKKLVE VKNVSLTFNK GKANQVKAID NVSFNIYEGE VFGLVGESGS GKTTIGRAIL
     KLYNIDKGEI DFEGETISKL KGKSLFNFRK KAQMIFQDPQ ASLNSRMKVR DIIAEGLDVH
     KLVKNKADRD AKVQDLLDLV GLNKDHLTRY PHEFSGGQRQ RIGIARALAV EPKFIIADEP
     ISALDVSIQA QVVNLMQKLQ HEQGLTYLFI AHDLSMVKYI SDRIGVMHWG KIVEIGTSDE
     VYHHPIHPYT QSLLSAVPEP DPVLERQRIH KVYDPVDELD GQEREMREIT PGHFVLATEE
     EAKAYKKK