ID   OPPF_STRP3              Reviewed;         307 AA.
AC   P0CZ32; P0A2V7; Q9F5U1;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Oligopeptide transport ATP-binding protein OppF;
GN   Name=oppF; OrderedLocusNames=SpyM3_0219;
OS   Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=198466;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-595 / MGAS315;
RX   PubMed=12122206; DOI=10.1073/pnas.152298499;
RA   Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D.,
RA   Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S.,
RA   Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
RT   "Genome sequence of a serotype M3 strain of group A Streptococcus: phage-
RT   encoded toxins, the high-virulence phenotype, and clone emergence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       oligopeptides. Probably responsible for energy coupling to the
CC       transport system (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; AE014074; AAM78826.1; -; Genomic_DNA.
DR   RefSeq; WP_002986000.1; NC_004070.1.
DR   AlphaFoldDB; P0CZ32; -.
DR   SMR; P0CZ32; -.
DR   EnsemblBacteria; AAM78826; AAM78826; SpyM3_0219.
DR   GeneID; 57852082; -.
DR   KEGG; spg:SpyM3_0219; -.
DR   HOGENOM; CLU_000604_1_23_9; -.
DR   OMA; VACHWAE; -.
DR   Proteomes; UP000000564; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR013563; Oligopep_ABC_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08352; oligo_HPY; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Peptide transport; Protein transport; Transport.
FT   CHAIN           1..307
FT                   /note="Oligopeptide transport ATP-binding protein OppF"
FT                   /id="PRO_0000092666"
FT   DOMAIN          6..251
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         42..49
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   307 AA;  34716 MW;  DB55C3F0E2FECDC6 CRC64;
     MSEKLVEVKD LEISFGEGKK KFVAVKNANF FIKKGETFSL VGESGSGKTT IGRAIIGLND
     TSSGQILYDG KVINGRKSKS EANELIRKIQ MIFQDPAASL NERATVDYII SEGLYNFNLF
     KTEEERKEKI KNMMAEVGLL SEHLTRYPHE FSGGQRQRIG IARALVMNPE FVIADEPISA
     LDVSVRAQVL NLLKRMQAEK GLTYLFIAHD LSVVRFISDR IAVIHKGVIV EVAETEELFN
     NPIHPYTQSL LSAVPIPDPI LERQKELVVY HPDQHDYTLD KPSMVEIKPN HFVWANQAEI
     EKYQKEL