ID   OPR6_ORYSJ              Reviewed;         391 AA.
AC   Q69TI2; A0A0N7KLR8;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Putative 12-oxophytodienoate reductase 6;
DE            EC=1.3.1.-;
DE   AltName: Full=OPDA-reductase 6;
DE            Short=OsOPR6;
GN   Name=OPR6; Synonyms=OPR4; OrderedLocusNames=Os06g0215500;
GN   ORFNames=OsJ_20590, OSJNBb0024N18.3, P0537F07.25;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- FUNCTION: Putative oxophytodienoate reductase that may be involved in
CC       the biosynthesis or metabolism of oxylipin signaling molecules.
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC   -!- SIMILARITY: Belongs to the NADH:flavin oxidoreductase/NADH oxidase
CC       family. {ECO:0000305}.
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DR   EMBL; AP003525; BAD35317.1; -; Genomic_DNA.
DR   EMBL; AP004741; BAD35825.1; -; Genomic_DNA.
DR   EMBL; AP008212; BAF19053.1; -; Genomic_DNA.
DR   EMBL; AP014962; BAS96777.1; -; Genomic_DNA.
DR   EMBL; CM000143; EAZ36269.1; -; Genomic_DNA.
DR   EMBL; AK108079; BAG98273.1; -; mRNA.
DR   RefSeq; XP_015641952.1; XM_015786466.1.
DR   AlphaFoldDB; Q69TI2; -.
DR   SMR; Q69TI2; -.
DR   STRING; 4530.OS06T0215500-01; -.
DR   PaxDb; Q69TI2; -.
DR   PRIDE; Q69TI2; -.
DR   EnsemblPlants; Os06t0215500-01; Os06t0215500-01; Os06g0215500.
DR   GeneID; 4340484; -.
DR   Gramene; Os06t0215500-01; Os06t0215500-01; Os06g0215500.
DR   KEGG; osa:4340484; -.
DR   eggNOG; KOG0134; Eukaryota.
DR   HOGENOM; CLU_012153_0_0_1; -.
DR   InParanoid; Q69TI2; -.
DR   OMA; QHRIGMA; -.
DR   OrthoDB; 978998at2759; -.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000007752; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   Genevisible; Q69TI2; OS.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009695; P:jasmonic acid biosynthetic process; IBA:GO_Central.
DR   GO; GO:0031408; P:oxylipin biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001155; OxRdtase_FMN_N.
DR   InterPro; IPR045247; Oye-like.
DR   PANTHER; PTHR22893; PTHR22893; 1.
DR   Pfam; PF00724; Oxidored_FMN; 1.
PE   2: Evidence at transcript level;
KW   Fatty acid biosynthesis; Fatty acid metabolism; Flavoprotein; FMN;
KW   Lipid biosynthesis; Lipid metabolism; NADP; Oxidoreductase;
KW   Oxylipin biosynthesis; Reference proteome.
FT   CHAIN           1..391
FT                   /note="Putative 12-oxophytodienoate reductase 6"
FT                   /id="PRO_0000410712"
FT   REGION          372..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..391
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        194
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   BINDING         42..44
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
FT   BINDING         75
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
FT   BINDING         117
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
FT   BINDING         189..192
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         241
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
FT   BINDING         282
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         312
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
FT   BINDING         333..334
FT                   /ligand="FMN"
FT                   /ligand_id="ChEBI:CHEBI:58210"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   391 AA;  43514 MW;  796DD6512B1FE8F7 CRC64;
     MVQHHQAAAN DDHQAIPLLT PYKQAGRPGS KLDLSHRVLL APMTRCRSYG NVPQPHAALY
     YTQRATRGGL LITEATGVSA TAQGYPETPG VRTREHVEAW KPIVDAVHRK GALFICQLWH
     VGRVSNNGFQ PDGLAPISST DKAITPDGYG MVYSKPRRLR TDEIPQIVDD FRLAARNAVE
     AGFDGVEIHG ANGYLLEQFM KDSSNDRTDE YGGSLENRCR FAVEVIDAVV GEIGAHSVGI
     RLSPFLDYMD CVDSDPEALG SYMVEQLNKH EDFLYCHMVE PRMAIVDGRR QIQHGLLPFR
     KQFNGTFIAA GGYDREEGNK AVADGYADLV AYGRLFLANP DLPKRFELDA PMNNYDRNTF
     YTQDPVVGYT DYPFLDEHHH DDDDDSNAPS A