ID   OPRR_PSEAE              Reviewed;         306 AA.
AC   Q01610;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   08-DEC-2000, sequence version 2.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Putative transcriptional regulator;
GN   OrderedLocusNames=PA2220;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-249.
RC   STRAIN=ATCC 15692 / PAO1 / H103;
RX   PubMed=1427017; DOI=10.1016/0378-1097(92)90347-q;
RA   Huang H., Siehnel R.J., Bellido F., Rawling E., Hancock R.E.W.;
RT   "Analysis of two gene regions involved in the expression of the imipenem-
RT   specific, outer membrane porin protein OprD of Pseudomonas aeruginosa.";
RL   FEMS Microbiol. Lett. 76:267-274(1992).
CC   -!- FUNCTION: May have a role in the regulation of oprD expression.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AE004091; AAG05608.1; -; Genomic_DNA.
DR   EMBL; Z14064; CAA78445.1; -; Genomic_DNA.
DR   PIR; A83369; A83369.
DR   PIR; S23859; S23859.
DR   RefSeq; NP_250910.1; NC_002516.2.
DR   RefSeq; WP_003113707.1; NZ_QZGE01000014.1.
DR   AlphaFoldDB; Q01610; -.
DR   SMR; Q01610; -.
DR   STRING; 208964.PA2220; -.
DR   PaxDb; Q01610; -.
DR   DNASU; 879199; -.
DR   EnsemblBacteria; AAG05608; AAG05608; PA2220.
DR   GeneID; 879199; -.
DR   KEGG; pae:PA2220; -.
DR   PATRIC; fig|208964.12.peg.2324; -.
DR   PseudoCAP; PA2220; -.
DR   HOGENOM; CLU_039613_16_1_6; -.
DR   InParanoid; Q01610; -.
DR   OMA; MVRRNLN; -.
DR   PhylomeDB; Q01610; -.
DR   BioCyc; PAER208964:G1FZ6-2260-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006351; P:transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..306
FT                   /note="Putative transcriptional regulator"
FT                   /id="PRO_0000105727"
FT   DOMAIN          1..61
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   306 AA;  34021 MW;  CF63FDC2706BBFA0 CRC64;
     MIKRNLNDLL SFVAVAREGT FTRAAAQLGV TQSALSQSIS GLEARLQIRL LTRTTRSVSP
     TAAGERLLNA IGNRFDEIEA ELDELSALRD KPSGTVRITC GDHIQRTLLL PRLTPLLLEY
     PDIKVEFDIN YGFRDIVADR FDAGVRLGDT IDKDMIAVPI GPPVRMAVVA APAYFAAHPK
     PRSPRDLVDH NCINMRMQSG GGLYAWDFQR KDRHVNVRVD GQLIFNTSPN IVDAALAGLG
     IAWLPEEEFA PHIEEGRLLR VLENWCPLFP GYYLYYPNRR QPSPAFSLVV DALRYTRPRG
     TTIGGG