AS126_ANOSM
ID AS126_ANOSM Reviewed; 114 AA.
AC A6P331;
DT 29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 23-FEB-2022, entry version 14.
DE RecName: Full=As-peptide 126 {ECO:0000312|EMBL:BAF65255.1};
DE Short=As-126 {ECO:0000303|PubMed:11992505};
DE Short=As126 {ECO:0000312|EMBL:BAF65255.1};
DE Flags: Precursor;
OS Anoplius samariensis (Solitary wasp).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Pompiloidea;
OC Pompilidae; Pompilinae; Anoplius.
OX NCBI_TaxID=200614;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Hisada M., Kanda A., Kuroda K., Minakata H., Nakajima T.;
RT "Cloning of alpha-pompilidotoxin and As126 cDNA in Anoplius samariensis.";
RL Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 105-113, SUBCELLULAR LOCATION, MASS SPECTROMETRY,
RP PYROGLUTAMATE FORMATION AT GLN-105, AND AMIDATION AT LYS-113.
RC TISSUE=Venom;
RX PubMed=11992505; DOI=10.1002/rcm.677;
RA Hisada M., Konno K., Itagaki Y., Naoki H., Nakajima T.;
RT "Sequencing wasp venom peptides by endopeptidase digestion and nested
RT collision-induced dissociation/post-source decay methods.";
RL Rapid Commun. Mass Spectrom. 16:1040-1048(2002).
RN [3]
RP REVIEW.
RX PubMed=27096870; DOI=10.3390/toxins8040114;
RA Konno K., Kazuma K., Nihei K.;
RT "Peptide toxins in solitary wasp venoms.";
RL Toxins 8:114-114(2016).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11992505}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:11992505}.
CC -!- MASS SPECTROMETRY: Mass=1022.5; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:11992505};
CC -!- MISCELLANEOUS: Is a minor component of A.samariensis venom.
CC {ECO:0000305|PubMed:27096870}.
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DR EMBL; AB087727; BAF65255.1; -; mRNA.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Pyrrolidone carboxylic acid; Repeat;
KW Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT PROPEP 23..104
FT /evidence="ECO:0000305"
FT /id="PRO_0000453649"
FT PEPTIDE 105..113
FT /note="As-peptide 126"
FT /evidence="ECO:0000269|Ref.1"
FT /id="PRO_5002697961"
FT REPEAT 22..29
FT /note="1"
FT /evidence="ECO:0000305"
FT REPEAT 30..37
FT /note="2"
FT /evidence="ECO:0000305"
FT REPEAT 38..45
FT /note="3"
FT /evidence="ECO:0000305"
FT REPEAT 46..53
FT /note="4"
FT /evidence="ECO:0000305"
FT REPEAT 54..61
FT /note="5"
FT /evidence="ECO:0000305"
FT REPEAT 62..69
FT /note="6"
FT /evidence="ECO:0000305"
FT REPEAT 70..77
FT /note="7"
FT /evidence="ECO:0000305"
FT REPEAT 78..85
FT /note="8"
FT /evidence="ECO:0000305"
FT REPEAT 86..93
FT /note="9"
FT /evidence="ECO:0000305"
FT REGION 22..93
FT /note="9 X 8 AA approximate tandem repeats of [AP]-[ILS]-
FT [AP]-A-A-N-A-[DE]"
FT /evidence="ECO:0000305"
FT REGION 82..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 105
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000269|PubMed:11992505"
FT MOD_RES 113
FT /note="Lysine amide"
FT /evidence="ECO:0000269|PubMed:11992505"
SQ SEQUENCE 114 AA; 10723 MW; 5206986316E062F0 CRC64;
MSRALICSLA LLAMLVISGT YASPAANAEA LAAANAEASA AANAEPLAAA NAEPLAAANA
EPLAAANADP IAAANAEPSA AANAEPLAAA NAEPSAGPSP LAAAQDPPVV KMKG
