ID   AS1AB_XENLA             Reviewed;         200 AA.
AC   Q7T0M6;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Histone chaperone asf1a-B;
DE   AltName: Full=Anti-silencing function protein 1 homolog A-B;
GN   Name=asf1ab; Synonyms=asf1a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Histone chaperone that facilitates histone deposition and
CC       histone exchange and removal during nucleosome assembly and
CC       disassembly. {ECO:0000250|UniProtKB:Q9Y294}.
CC   -!- SUBUNIT: Interacts with histone H3 (including both histone H3.1 and
CC       H3.3) and histone H4. {ECO:0000250|UniProtKB:Q9Y294}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y294}.
CC   -!- SIMILARITY: Belongs to the ASF1 family. {ECO:0000305}.
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DR   EMBL; BC056123; AAH56123.1; -; mRNA.
DR   RefSeq; NP_001080310.1; NM_001086841.1.
DR   AlphaFoldDB; Q7T0M6; -.
DR   SMR; Q7T0M6; -.
DR   BioGRID; 98244; 1.
DR   DNASU; 380002; -.
DR   GeneID; 380002; -.
DR   KEGG; xla:380002; -.
DR   CTD; 380002; -.
DR   Xenbase; XB-GENE-6256602; asf1b.L.
DR   OMA; SCTPVKG; -.
DR   OrthoDB; 1334998at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 380002; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1490; -; 1.
DR   InterPro; IPR006818; ASF1-like.
DR   InterPro; IPR036747; ASF1-like_sf.
DR   PANTHER; PTHR12040; PTHR12040; 1.
DR   Pfam; PF04729; ASF1_hist_chap; 1.
DR   SUPFAM; SSF101546; SSF101546; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Chromatin regulator; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..200
FT                   /note="Histone chaperone asf1a-B"
FT                   /id="PRO_0000284021"
SQ   SEQUENCE   200 AA;  22413 MW;  48CA7A6D0A7AFFF6 CRC64;
     MAKVQILNMV VLDNPCPFHN PFQFEITFEC IEDLPDDLEW KIIYVGSAES EEYDQTLDSV
     LVGPVPAGRH MFVFQADAPN CSLIPESDAV GVTVVLITCT YRGQEFIRVG YYVNNEYSDP
     ELRENPPLKA HFGQLQRNIL ASNPRVTRFH INWECTSEAK MEDIENVDPA SNTMLPPNCA
     PSKGLAAALN TLPENSMDCM