ID   ASA1_ASHGO              Reviewed;         395 AA.
AC   Q75BE7;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; OrderedLocusNames=ADL383W; ORFNames=AGOS_ADL383W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51537.1; -; Genomic_DNA.
DR   RefSeq; NP_983713.1; NM_209066.1.
DR   AlphaFoldDB; Q75BE7; -.
DR   STRING; 33169.AAS51537; -.
DR   EnsemblFungi; AAS51537; AAS51537; AGOS_ADL383W.
DR   GeneID; 4620009; -.
DR   KEGG; ago:AGOS_ADL383W; -.
DR   eggNOG; ENOG502QU4T; Eukaryota.
DR   HOGENOM; CLU_045414_1_0_1; -.
DR   InParanoid; Q75BE7; -.
DR   OMA; LVCCNTQ; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..395
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402201"
FT   REPEAT          7..48
FT                   /note="WD 1"
FT   REPEAT          221..260
FT                   /note="WD 2"
FT   REPEAT          343..386
FT                   /note="WD 3"
SQ   SEQUENCE   395 AA;  44616 MW;  44D021FE1F9F31D9 CRC64;
     MRFTLRAHVS TVTDLKPVSH RQTPHLLSAD SKGCLYLWNL ISRRPIASID LKTHIIAIEV
     VGQGLYAALA RDNKLRFISL QEESRLTRIN DKVSRELQSL EIVYEIPVNC LNFANFALQD
     LGLRNYRLWC CNTMDAESID VYEFQLGDRQ SFKRTFNAIN LFDSVAGLAE AKQKFRFDKM
     GIVMRFIVAG DTVFCGYESG VVVGLRIRDK SLQICYASFA HYPEPVLSLA HDRTERRVFS
     SSTTDQVCVH NIPTPDLPVV TSVSGIQVVA NAGTREEVIN APLKKIGHLA VLNDILLLTS
     WHGYVLGLQD QKELFRYRKE RNLLCVDDST DGQAETKKEK PWINPGPIAG IAHSTDSQLV
     LEKLPIGGHR RLKNFLEHKW YITGYNDGTI TVSQI