ID   A2AP_STRCA              Reviewed;          11 AA.
AC   P83168;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   11-DEC-2019, entry version 45.
DE   RecName: Full=Alpha-2-antiplasmin;
DE            Short=Alpha-2-AP;
DE   AltName: Full=Alpha-2-plasmin inhibitor;
DE            Short=Alpha-2-PI;
DE   AltName: Full=Serpin F2;
DE   Flags: Fragment;
GN   Name=SERPINF2;
OS   Struthio camelus (Common ostrich).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=8801;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RC   TISSUE=Plasma {ECO:0000269|PubMed:11435135};
RX   PubMed=11435135; DOI=10.1016/s1096-4959(01)00396-7;
RA   Thomas A.R., Naude R.J., Oelofsen W., Naganuma T., Muramoto K.;
RT   "Purification and partial characterisation of alpha(2)-antiplasmin and
RT   plasmin(ogen) from ostrich plasma.";
RL   Comp. Biochem. Physiol. 129B:809-820(2001).
CC   -!- FUNCTION: Serine protease inhibitor. The major targets of this
CC       inhibitor are plasmin and trypsin, but it also inactivates matriptase-
CC       3/TMPRSS7 and chymotrypsin. {ECO:0000269|PubMed:11435135}.
CC   -!- SUBUNIT: Forms protease inhibiting heterodimer with TMPRSS7.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the serpin family. {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; NAS:UniProtKB.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Protease inhibitor; Secreted;
KW   Serine protease inhibitor.
FT   CHAIN           1..>11
FT                   /note="Alpha-2-antiplasmin"
FT                   /id="PRO_0000094125"
FT   NON_TER         11
FT                   /evidence="ECO:0000303|PubMed:11435135"
SQ   SEQUENCE   11 AA;  1261 MW;  9B08C06B32C73B5A CRC64;
     LQVDYLVLEV A