ID   ASA1_ASPFN              Reviewed;         429 AA.
AC   B8NG55;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=asa1; ORFNames=AFLA_132160;
OS   Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS   / JCM 12722 / SRRC 167).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=332952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC
RC   167;
RX   PubMed=25883274; DOI=10.1128/genomea.00168-15;
RA   Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA   Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT   "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT   aflatoxin contamination of food and feed.";
RL   Genome Announc. 3:E0016815-E0016815(2015).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; EQ963478; EED50454.1; -; Genomic_DNA.
DR   RefSeq; XP_002379230.1; XM_002379189.1.
DR   AlphaFoldDB; B8NG55; -.
DR   STRING; 5059.CADAFLAP00007095; -.
DR   EnsemblFungi; EED50454; EED50454; AFLA_132160.
DR   VEuPathDB; FungiDB:AFLA_132160; -.
DR   eggNOG; KOG0322; Eukaryota.
DR   HOGENOM; CLU_041940_0_1_1; -.
DR   OMA; AWDLTIM; -.
DR   Proteomes; UP000001875; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 3.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Repeat; WD repeat.
FT   CHAIN           1..429
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402202"
FT   REPEAT          19..58
FT                   /note="WD 1"
FT   REPEAT          64..104
FT                   /note="WD 2"
FT   REPEAT          208..250
FT                   /note="WD 3"
FT   REPEAT          270..314
FT                   /note="WD 4"
FT   REPEAT          315..354
FT                   /note="WD 5"
FT   REPEAT          392..429
FT                   /note="WD 6"
FT   REGION          148..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..171
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   429 AA;  47384 MW;  327222F322396417 CRC64;
     MSTPTQLQPP ASPTYILRGH ASPIHGLHIF HQNLRLISGD ADGWIIVWDL VFKRPVAVWK
     AHEGAILEVK GFTFSNQTVT EVYTHGRDHK LCVWRFRAQD EDLLQKTLPV DISEQNQSQA
     TQPWLVHSLP VNALNFCAFS MLFLDEEESP DTGEPEASDK TSTQSPGKNP PQHHSLFAVP
     NALNSGAIDI FHLPRERRLC TIPADQTTQT GMVMAVTLFY SSTRELYIAS AYEDGHVMVF
     ALRGQLTTQD FSGKASSDSW KWERVYVARA HSQPALSIDV FPAGGYFVSS SADALVVKHP
     VPGFGEVGTV KKVDTKHSGQ QGVRIRSDGR VFATAGWDSR VRVYSCKTLR ELAVLKWHKE
     GCYTVAFADV EGSFDSGGGA TGDGDGAQVT KSGEFSLATV RRQRNQKVQK THWLAAGSKD
     GKISLWDIY