ID   ASA1_CANAL              Reviewed;         377 AA.
AC   Q5ABV4; A0A1D8PQ30; Q5AC76;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2017, sequence version 2.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; OrderedLocusNames=CAALFM_C603110CA;
GN   ORFNames=CaO19.13041, CaO19.5596;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; CP017628; AOW30242.1; -; Genomic_DNA.
DR   RefSeq; XP_719157.2; XM_714064.2.
DR   AlphaFoldDB; Q5ABV4; -.
DR   SMR; Q5ABV4; -.
DR   STRING; 237561.Q5ABV4; -.
DR   GeneID; 3639278; -.
DR   KEGG; cal:CAALFM_C603110CA; -.
DR   CGD; CAL0000191787; orf19.13041.
DR   VEuPathDB; FungiDB:C6_03110C_A; -.
DR   eggNOG; KOG0322; Eukaryota.
DR   HOGENOM; CLU_045414_0_0_1; -.
DR   InParanoid; Q5ABV4; -.
DR   OrthoDB; 1543596at2759; -.
DR   PRO; PR:Q5ABV4; -.
DR   Proteomes; UP000000559; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..377
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402204"
FT   REPEAT          10..50
FT                   /note="WD 1"
FT   REPEAT          53..90
FT                   /note="WD 2"
FT   REPEAT          230..262
FT                   /note="WD 3"
FT   REPEAT          263..303
FT                   /note="WD 4"
FT   REPEAT          342..377
FT                   /note="WD 5"
SQ   SEQUENCE   377 AA;  42568 MW;  44F05259226280D9 CRC64;
     MLSTKFTLRS HKSSVAYIYQ DPRTPFNLFT ADSSGLIINW DLTIRRPKKS WQAHTDTILT
     ISTIHNHLLT HSRDNTIKIW DESYSCVLEI PCNALNFSNI CIIYDLLITP ASINSNNLDV
     YKIDKDWQIT RLISDFDVYK LVNKGEIIEE IGSSGTSRND FGIIMQMKII HTNTTTTTSE
     NNSDYIIYVG FESGDIVGLQ LILPRARILS TTGNTNDKTL INQSAKFILQ YHNSTHVPNP
     VICLSNLDSV LVSGSTTNKV IIHSDPIEIM KMDHSGIQAI VNFKNDRLIF GYWNGYIQYG
     DISINQSLPK LGNTEQEKSK LTKKLTFMTI LNESNQETLQ SPTGKSKYLA LLKSKRNLVF
     PLLLAGYEDG SILAYNI