ASA1_CANTT
ID ASA1_CANTT Reviewed; 356 AA.
AC C5MH59;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=ASTRA-associated protein 1;
GN Name=ASA1; ORFNames=CTRG_05413;
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC remodeling. {ECO:0000250}.
CC -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR EMBL; GG692402; EER30961.1; -; Genomic_DNA.
DR RefSeq; XP_002551115.1; XM_002551069.1.
DR AlphaFoldDB; C5MH59; -.
DR SMR; C5MH59; -.
DR STRING; 5482.XP_002551115.1; -.
DR EnsemblFungi; EER30961; EER30961; CTRG_05413.
DR GeneID; 8299738; -.
DR KEGG; ctp:CTRG_05413; -.
DR VEuPathDB; FungiDB:CTRG_05413; -.
DR eggNOG; ENOG502QU4T; Eukaryota.
DR HOGENOM; CLU_045414_0_0_1; -.
DR OrthoDB; 1543596at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..356
FT /note="ASTRA-associated protein 1"
FT /id="PRO_0000402208"
FT REPEAT 9..49
FT /note="WD 1"
FT REPEAT 52..89
FT /note="WD 2"
FT REPEAT 210..242
FT /note="WD 3"
FT REPEAT 243..283
FT /note="WD 4"
FT REPEAT 317..356
FT /note="WD 5"
SQ SEQUENCE 356 AA; 40438 MW; DBD60CE7B1F3F7B7 CRC64;
MSQQFTLRSH NSSITFIYPS PTSSLHLYTA DSTGLIIEWD LITRRPVITW QAHNDTILSM
STIHNHLLTH SRDNTIKIWN NTDCIMEIPC NSLNFSNVVV VHDEILITPA SINSNNLDVY
KITSDWQLTR LISDINVYQL VEKGIQFEEI GSRNDYGIIM KIHLVDNIIY VGFESGDIVG
LELILPKPIV KENSNIDKLI INQSPKLIVK YHNSIHVPNP IISMSTFQDI LVSGSTTNKI
VIHKHPVEII KVTHSGVQSI VNYKNENLII GFWNGEIRYD ENVIKRDVPM IQNNDNDDRS
KSIKKLTFMT LLVPQKVEST TTGKNKYSQL IRGKKILTTD TLLVGYEDGS IVAYKV
