ID   ASA1_CLAL4              Reviewed;         360 AA.
AC   C4YBE4;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; ORFNames=CLUG_05522;
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; CH408082; EEQ41394.1; -; Genomic_DNA.
DR   RefSeq; XP_002614744.1; XM_002614698.1.
DR   AlphaFoldDB; C4YBE4; -.
DR   SMR; C4YBE4; -.
DR   STRING; 306902.C4YBE4; -.
DR   EnsemblFungi; EEQ41394; EEQ41394; CLUG_05522.
DR   GeneID; 8495102; -.
DR   KEGG; clu:CLUG_05522; -.
DR   VEuPathDB; FungiDB:CLUG_05522; -.
DR   HOGENOM; CLU_045414_0_0_1; -.
DR   InParanoid; C4YBE4; -.
DR   OMA; PHEQIEA; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..360
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402209"
FT   REPEAT          9..46
FT                   /note="WD 1"
FT   REPEAT          49..86
FT                   /note="WD 2"
FT   REPEAT          167..205
FT                   /note="WD 3"
FT   REPEAT          317..357
FT                   /note="WD 4"
SQ   SEQUENCE   360 AA;  39342 MW;  D9175B4BCC92BF82 CRC64;
     MEKMFSLRAH AAPVSGFCPW ENQLVSADRS GTLIVWNLST RRPAARFRAH EGQVLSMQPT
     RFGLLTHGRD SAVRIWPPGA AENSKGGDPH PIFEMPVNAL NFCNVAYIDG ADGTALLATP
     ASVDSDCFDV YRLSPDFSLA RAVENQAPKQ EQRGADQIEE IGAPPGRGEG IIMRLAWAAP
     DLLYVGYESG ALASFSLSPE GCRMLWLARA HSPHPVLSLA LEGARVYSGS AAKTLLVHEP
     PHEEAVAKHN LGHYGVQCFE ILPHLYLAGF WDGSVAGFSR DWQQLFSLER PHEQIEAPES
     PSRKSLCLFV WSAPAAPEQS RRDRLRSRRA AGRLLFVGHA DGLIVAYAID ESSENGLLES