ID   ASA1_DEBHA              Reviewed;         476 AA.
AC   Q6BPL7;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 2.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=ASTRA-associated protein 1;
GN   Name=ASA1; OrderedLocusNames=DEHA2E12606g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC       remodeling. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR   EMBL; CR382137; CAG88094.2; -; Genomic_DNA.
DR   RefSeq; XP_459853.2; XM_459853.1.
DR   AlphaFoldDB; Q6BPL7; -.
DR   STRING; 4959.XP_459853.2; -.
DR   EnsemblFungi; CAG88094; CAG88094; DEHA2E12606g.
DR   GeneID; 2902675; -.
DR   KEGG; dha:DEHA2E12606g; -.
DR   VEuPathDB; FungiDB:DEHA2E12606g; -.
DR   eggNOG; KOG0322; Eukaryota.
DR   HOGENOM; CLU_045414_0_0_1; -.
DR   InParanoid; Q6BPL7; -.
DR   OMA; WHNSENG; -.
DR   OrthoDB; 1543596at2759; -.
DR   Proteomes; UP000000599; Chromosome E.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   SMART; SM00320; WD40; 5.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..476
FT                   /note="ASTRA-associated protein 1"
FT                   /id="PRO_0000402210"
FT   REPEAT          11..52
FT                   /note="WD 1"
FT   REPEAT          55..93
FT                   /note="WD 2"
FT   REPEAT          132..176
FT                   /note="WD 3"
FT   REPEAT          313..352
FT                   /note="WD 4"
FT   REPEAT          362..399
FT                   /note="WD 5"
FT   REPEAT          441..476
FT                   /note="WD 6"
SQ   SEQUENCE   476 AA;  54339 MW;  8047757A683CEF31 CRC64;
     MKPIELCTLR GHLNDITCTE PYYIGGKVSL VSADSNGWII WWDINTRRPN CVWKGHDSNI
     VTLRQICNGL LLTHSKDSDI KIWDVENFKS GSREMPAEKY NNVQYFSIDR DGEEDNNVSK
     NELLEAFPLP ENVVIPVNAL NYCNVDYSNH HLITPATTDS NNFDLYSIFK PSHQTDESLE
     AKLNLKRVAA NIDPWKLYKK TITQLNKEQG VEFEIGNEND ILKRDKFGIM MKVLFVRDDL
     FYIGYESGHL IGYHIDFSGA INNENEGAKS DSVKPDKNVS GLAGLFGNKT KSFDKTIINK
     DPHIKMIYMN DSCSPYPIIS LVYDNKENKI ICGSAGKQLT FHKIPEEFSQ FNDISDCKRY
     NLRHSGIQSV SINNSLLVVG FWDGLIKGYD LDLNELFKYC KRLPRIDVLE SNSGQQQPRE
     KQNSIKLCTV KLVIPNETDV VKSNDYKSLI KHKRDITTTN LLISSYYDGT ITIFKV